The Ly-49A is a 44 kDa, type II transmembrane protein with disulfide-linked homodimers and external C-type lectin domains.
| Inventor | Institute |
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| Fumio Takei | BC Cancer |
| SKU: | 160512 |
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| Product description: | The Ly-49A is a 44 kDa, type II transmembrane protein with disulfide-linked homodimers and external C-type lectin domains. Ly-49A is present on the surface of mouse NK cells with the purpose to inhibit NK cell activation by recognition and interaction with certain MHC-1s on target cells. The Ly-49A receptor recognizes H-2Dd and H-2Dk. |
| Conjugation: | Unconjugated |
| Molecular weight: | 44 kDa |
| Immunogen: | ECA17.9.8 cells |
| Myeloma used: | Y3 |
| Cat. #: | 160512 |
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| Tool sub type: | Primary antibody |
| Unit size: | 100 ug |
| Research Fields: | Cancer; Immunology |
| Application: | IP ; FACS |
| Target: | Ly-49A |
| Reactivity: | Mouse |
| Host: | Rat |
| Class: | Monoclonal |
| Target background: | The Ly-49A is a 44 kDa, type II transmembrane protein with disulfide-linked homodimers and external C-type lectin domains. Ly-49A is present on the surface of mouse NK cells with the purpose to inhibit NK cell activation by recognition and interaction with certain MHC-1s on target cells. The Ly-49A receptor recognizes H-2Dd and H-2Dk. |
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| Format: | Liquid |
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| Shipping conditions: | Dry ice |
| References: |
Takei et al. 1997. Immunol Rev. 155:67-77. PMID: 9059883. Chan et al. 1989. J Immunol. 142(5):1727-36. PMID: 2783949. Takei et al. 1983. J Immunol. 130(6):2794-7. PMID: 6304191. |
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