Anti-KPNB1

Anti importin beta1 KPNB1 monoclonal antibody (mAbKPNB1-301-320) is a nucleocytoplasmic transport factor with critical roles in both cytoplasmic and nucleocytoplasmic transport.

Contributors

Inventor Institute
Michael Fainzilber, Ida Rishal, Ella Doron-Mandel, Stefanie Alber, Didi-Andreas Song Weizmann Institute of Science
SKU: 161730
Product description: Anti importin beta1 (KPNB1) is a nucleocytoplasmic transport factor with critical roles in both cytoplasmic and nucleocytoplasmic transport. It has been implicated in cancer in a number of studies, including glioblastoma, epithelial ovarian cancer, gastric cancer and cervical cancer. It was also shown to be important in axonal injury signalling activate regeneration programs in neuronal cell bodies
Alternate name: mAbKPNB1-301-320
Additional notes: The epitope sequence has been mapped to a 20 amino acid linear sequence comprising residues 301-320 of human KPBN1. A synthetic peptide with this sequence can be used as a blocking control for antibody specificity
Conjugation: No
Isotype: IgG2b
Molecular weight: 97.170 kDa
Immunogen: The antibody was raised against full-length recombinant mouse importin ?1 protein (UniProt accession # P70168). The protein included an N-terminal His-tag and was produced in yeast (MyBioSource: cat # MBS955236).
Immunogen Uniprot ID: Q99KM9
Cat. #: 161730
Tool sub type: Primary antibody
Unit size: 100 ug
Research Fields: Cell signaling and signal transduction; Genetics
Application: IHC;IF; Electron microscopy (EM); IP; WB; Biotinylation by Antibody Recognition (BAR), ELISA; Proximity ligation assay (PLA)
Target: Karyopherin Subunit Beta 1 (KPNB1)
Reactivity: Human, mouse, rat, bovine
Clone: KPNB1
Host: Mouse
Class: Monoclonal
Primary citation: Didi-Andreas Song, et al. 2022. Mol Cell Proteomics. 21(11):100418. PMID: 36180036
Target background: Importin ?1 (KPNB1) is a nucleocytoplasmic transport factor with critical roles in both cytoplasmic and nucleocytoplasmic transport
Concentration: 1mg/ml
Storage buffer: PBS with 0.02% azide
Storage conditions: -15° C to -25° C
Shipping conditions: Dry ice
References:

Didi-Andreas Song, et al. 2022. Mol Cell Proteomics. 21(11):100418. PMID: 36180036

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