LL020 can be used as a proliferation marker.
| Inventor | Institute |
|---|---|
| Irene Leigh | Cancer Research UK, London Research Institute: Clare Hall Laboratories |
| SKU: | 151122 |
|---|---|
| Product description: | LL020 can be used as a proliferation marker. |
| Conjugation: | Unconjugated |
| Isotype: | IgM |
| Molecular weight: | 50 kDa |
| Immunogen: | Carboxy terminal peptide |
| Myeloma used: | Sp2/0-Ag14 |
| Cat. #: | 151122 |
|---|---|
| Provenance and Ownership: | The Anti-Keratin6 [LL020] is owned by Cancer Research UK. CancerTools supplies the Anti-Keratin6 [LL020] under licence from Cancer Research UK and is the authorised source for its distribution. Sourcing Anti-Keratin6 [LL020] directly from the IP owner ensures authenticity, provenance and compliance with all applicable licensing and research use requirements. |
| Tool sub type: | Primary antibody |
| Unit size: | 100 ug |
| Research Fields: | Cell signaling and signal transduction |
| Application: | IHC ; IF ; WB |
| Target: | Keratin 6 |
| Reactivity: | Human |
| Clone: | LL020 |
| Host: | Mouse |
| Class: | Monoclonal |
| Target background: | Keratins are a family of intermediate filament proteins that assemble into filaments through forming heterodimers of one type I keratin (keratins 9 to 23) and one type II keratin (keratins 1 to 8). Keratins demonstrate tissue and differentiation specific expression profiles. Keratins 6 is expressed in suprabasal keratinocytes of wounded epidermis and in acrosyringeal keratinocytes in normal skin. |
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| Format: | Liquid |
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| Concentration: | 0.9-1.1 mg/ml |
| Storage buffer: | PBS with 0.02% azide |
| Storage conditions: | -15° C to -25° C |
| Shipping conditions: | Dry ice |
| References: |
Hughes et al. 1996. Br J Dermatol. 134(2):247-56. PMID: 8746337. Keratin expression in pilosebaceous epithelia in truncal skin of acne patients. Markey et al. 1992. Br J Dermatol. 126(2):154-60. PMID: 1371396. Keratin expression in basal cell carcinomas. |
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