Cytokeratin 14 is a member of the type I keratin family of intermediate filament proteins. Cytokeratin 14 is usually found as a heterodimer with type II keratin 5 and form the cytoskeleton of epithelial cells.
| Institute |
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| Netherlands Cancer Institute |
| SKU: | 154748 |
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| Product description: | Cytokeratin 14 is a member of the type I keratin family of intermediate filament proteins. Cytokeratin 14 is usually found as a heterodimer with type II keratin 5 and form the cytoskeleton of epithelial cells. Mutations in the genes for these keratins are associated with epidermolysis bullosa simplex and dermatopathia pigmentosa reticularis, both of which are autosomal dominant mutations |
| Alternate name: | KRT14; Keratin 14 |
| Conjugation: | Unconjugated |
| Isotype: | IgG1 |
| Molecular weight: | 51 kDa |
| Immunogen: | Mouse was immunized with a synthetic peptide corresponding to the carboxy-terminal sequence of human cytokeratin 14 (KVVSTHEQVLRTKN) coupled to keyhole limpet hemocyanin. |
| Myeloma used: | Sp2/0-Ag14 |
| Cat. #: | 154748 |
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| Tool sub type: | Primary antibody |
| Unit size: | 100 ug |
| Research Fields: | Cell biology |
| Application: | FACS ; IHC ; WB |
| Target: | Keratin14 |
| Reactivity: | Human ; Pig ; Feline |
| Host: | Mouse |
| Class: | Monoclonal |
| Target background: | Cytokeratin 14 is a member of the type I keratin family of intermediate filament proteins. Cytokeratin 14 is usually found as a heterodimer with type II keratin 5 and form the cytoskeleton of epithelial cells. Mutations in the genes for these keratins are associated with epidermolysis bullosa simplex and dermatopathia pigmentosa reticularis, both of which are autosomal dominant mutations |
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| Format: | Liquid |
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| Concentration: | 0.9-1.1 mg/ml |
| Storage buffer: | PBS with 0.02% azide |
| Storage conditions: | -15° C to -25° C |
| Shipping conditions: | Dry ice |
| References: |
Ivanyi et al. 1993. Am J Vet Res. 54(7):1095-102. PMID: 7690208. Ivanyi et al. 1992. Am J Vet Res. 53(3):304-14. PMID: 1375818. |
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