Irisin belongs to the class of adipomyokines since it acts both in adipose and muscle tissue (adipokine and myokine) and is a thermogenic protein that promotes energy expenditure by white adipose tissue (WAT) browning. Irisin is secreted from muscles in response to exercise and may mediate some beneficial effects of exercise in humans, such as weight loss and thermoregulation. Irisin is a cleavage protein of fibronectin type III domain 5 (FNDC5). FNDC5 converts to irisin after exercise. Irisin dissipates energy as heat and for this reason its discovery has generated a flurry of research aimed at understanding the mechanisms of…
| Inventor | Institute |
|---|---|
| Abdo Alnabulsi | Vertebrate Antibodies Limited |
| SKU: | 158034 |
|---|---|
| Product description: | Irisin belongs to the class of adipomyokines since it acts both in adipose and muscle tissue (adipokine and myokine) and is a thermogenic protein that promotes energy expenditure by white adipose tissue (WAT) browning. Irisin is secreted from muscles in response to exercise and may mediate some beneficial effects of exercise in humans, such as weight loss and thermoregulation. Irisin is a cleavage protein of fibronectin type III domain 5 (FNDC5). FNDC5 converts to irisin after exercise. Irisin dissipates energy as heat and for this reason its discovery has generated a flurry of research aimed at understanding the mechanisms of energy metabolism. Irisin is expected to be a potential therapeutic agent for the treatment of obesity and its related conditions. This tool is significant as the peptide immunogen used to generate antibodies is conserved across all vertebrates. |
| Conjugation: | Unconjugated |
| Isotype: | IgG |
| Molecular weight: | 12 |
| Immunogen: | Ovalbumin-conjugated synthetic peptide. Peptide immunogen is conserved across all vertebrates. |
| Cat. #: | 158034 |
|---|---|
| Unit size: | 100 ug |
| Research Fields: | Cell biology;Immunology |
| Application: | ELISA ; IHC ; WB |
| Target: | Irisin |
| Reactivity: | Human |
| Host: | Mouse |
| Class: | Monoclonal |
| Target background: | Irisin belongs to the class of adipomyokines since it acts both in adipose and muscle tissue (adipokine and myokine) and is a thermogenic protein that promotes energy expenditure by white adipose tissue (WAT) browning. Irisin is secreted from muscles in response to exercise and may mediate some beneficial effects of exercise in humans, such as weight loss and thermoregulation. Irisin is a cleavage protein of fibronectin type III domain 5 (FNDC5). FNDC5 converts to irisin after exercise. Irisin dissipates energy as heat and for this reason its discovery has generated a flurry of research aimed at understanding the mechanisms of energy metabolism. Irisin is expected to be a potential therapeutic agent for the treatment of obesity and its related conditions. This tool is significant as the peptide immunogen used to generate antibodies is conserved across all vertebrates. |
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| Format: | Liquid |
|---|---|
| Shipping conditions: | Dry ice |
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| 151036 | Anti-ICAM1 [15.2] |
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| 151030 | Anti-Progesterone [11P14] |
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