ITGA3 is an integrin alpha subunit. Together with beta-1 subunit, it makes up half of the a3?1 integrin duplex that plays a role in neural migration and corticogenesis, acted upon by such factors as netrin-1 and reelin.
| Inventor | Institute |
|---|---|
| Arnoud Sonnenberg | Netherlands Cancer Institute |
| SKU: | 154744 |
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| Product description: | ITGA3 is an integrin alpha subunit. Together with beta-1 subunit, it makes up half of the ÄÂ?3ÄÂ?1 integrin duplex that plays a role in neural migration and corticogenesis, acted upon by such factors as netrin-1 and reelin. |
| Alternate name: | ITGA3; Antigen CD61 |
| Conjugation: | Unconjugated |
| Isotype: | IgG1 |
| Immunogen: | A mouse was immunized with a synthetic peptide corresponding to a 32 amino acid stretch in the cytoplasmic domain of integrin a3B including an appending N-terminal cysteine (CTRYYQIMPKYHAVRIREEERYPPPGSTLPTKK) coupled to keyhole limpet hemocyanin. |
| Myeloma used: | Sp2/0-Ag14 |
| Cat. #: | 154744 |
|---|---|
| Tool sub type: | Primary antibody |
| Unit size: | 100 ug |
| Research Fields: | Cell biology; Cell signaling and signal transduction |
| Application: | IHC ; WB |
| Target: | Integrin a3B |
| Reactivity: | Human |
| Host: | Mouse |
| Class: | Monoclonal |
| Target background: | ITGA3 is an integrin alpha subunit. Together with beta-1 subunit, it makes up half of the a3?1 integrin duplex that plays a role in neural migration and corticogenesis, acted upon by such factors as netrin-1 and reelin. |
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| Format: | Liquid |
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| Concentration: | 0.9-1.1 mg/ml |
| Storage buffer: | PBS with 0.02% azide |
| Storage conditions: | -15° C to -25° C |
| Shipping conditions: | Dry ice |
| References: |
de Melker et al. 1997. Lab Invest. 76(4):547-63. PMID: 9111516. |
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