This anti-IgM antibody provides a useful tool to monitor brood stock health and vaccine efficacy in fish and will assist in the development of future vaccines.
| Inventor | Institute |
|---|---|
| Abdo Alnabulsi | Vertebrate Antibodies Limited |
| SKU: | 158052 |
|---|---|
| Product description: | IGHM (Immunoglobulin heavy constant Mu) is a protein coding gene. The IGHM gene encodes the C region of the mu heavy chain, which defines the Immunoglobulin (Ig) M isotype. Immunoglobulin is membrane-bound or is secreted as glycoproteins produced by B lymphocytes. In the recognition phase of humoral immunity, the membrane-bound immunoglobulin serves as a receptor which, upon binding of a specific antigen, triggers the clonal expansion and differentiation of B lymphocytes into immunoglobulin-secreting plasma cells. Secreted immunoglobulin mediates the effector phase of humoral immunity, which results in the elimination of bound antigens. Detection of specific antibodies in the serum of animals is an indicator of previous exposure to pathogens which is very valuable for brood-stocks health testing.This anti-IgM antibody provides a useful tool to monitor brood stock health and vaccine efficacy in fish and will assist in the development of future vaccines. |
| Conjugation: | Unconjugated |
| Molecular weight: | 68 kDa |
| Immunogen: | Ovalbumin-conjugated synthetic peptide. Peptide immunogen is specific to Pangasius catfish specie. |
| Cat. #: | 158052 |
|---|---|
| Tool sub type: | Secondary antibody |
| Unit size: | 100 ug |
| Cancer types: | Other |
| Research Fields: | Cell biology; Immunology |
| Application: | ELISA |
| Target: | Immunoglobulin Heavy Constant Mu (IgM) |
| Reactivity: | Pangasius Catfish |
| Host: | Rabbit |
| Class: | Polyclonal |
| Target background: | IGHM (Immunoglobulin heavy constant Mu) is a protein coding gene. The IGHM gene encodes the C region of the mu heavy chain, which defines the Immunoglobulin (Ig) M isotype. Immunoglobulin is membrane-bound or is secreted as glycoproteins produced by B lymphocytes. In the recognition phase of humoral immunity, the membrane-bound immunoglobulin serves as a receptor which, upon binding of a specific antigen, triggers the clonal expansion and differentiation of B lymphocytes into immunoglobulin-s… |
|---|
| Format: | Liquid |
|---|---|
| Storage buffer: | Unpurified anti-serum from rabbit preserved in 0.02% Thiomersal |
| Shipping conditions: | Dry ice |
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