Anti-IGF

Insulin-like growth factor 1 (IGF-1) is produced by the liver and skeletal muscle as well as many other tissues in response to growth hormone (GH) stimulation. IGF-1 mediates many of the actions of GH, stimulating the growth of bones and other tissues and promoting the production of lean muscle mass. IGF-1 is a useful indicator of average GH levels. The IGF-1 test is therefore often used to help evaluate for GH deficiency or GH excess. IGF-1 deficiencies are seen early in life and are usually the result of GH deficiency. They can inhibit bone growth and overall development and can…

Contributors

Inventor Institute
Abdo Alnabulsi Vertebrate Antibodies Limited
SKU: 158051
Product description: Insulin-like growth factor 1 (IGF-1) is produced by the liver and skeletal muscle as well as many other tissues in response to growth hormone (GH) stimulation. IGF-1 mediates many of the actions of GH, stimulating the growth of bones and other tissues and promoting the production of lean muscle mass. IGF-1 is a useful indicator of average GH levels. The IGF-1 test is therefore often used to help evaluate for GH deficiency or GH excess. IGF-1 deficiencies are seen early in life and are usually the result of GH deficiency. They can inhibit bone growth and overall development and can result in a child with a shorter than normal stature. In adults, decreased production can lead to low bone density, less muscle mass, and altered lipid levels. Insulin-like growth factor 1 (IGF-1) is an evolutionary conserved peptide, which has been shown to be essential in the regulation of body size, the pattern of reproductive investment and life span across a broad taxonomic range of model species in laboratory and domesticated conditions. However, studies addressing corresponding evolutionary hypotheses on a broader scale and in free-living vertebrates are very rare. This is a very useful research tool to monitor muscle development and metabolism in birds.
Conjugation: Unconjugated
Molecular weight: 17
Immunogen: Ovalbumin-conjugated synthetic peptide. Peptide immunogen is conserved in all bird species
Cat. #: 158051
Unit size: 100 ug
Research Fields: Cell biology;Immunology
Application: ELISA
Target: Insulin-like growth factor 1 (IGF)
Reactivity: Avian
Host: Rabbit
Class: Polyclonal
Target background: Insulin-like growth factor 1 (IGF-1) is produced by the liver and skeletal muscle as well as many other tissues in response to growth hormone (GH) stimulation. IGF-1 mediates many of the actions of GH, stimulating the growth of bones and other tissues and promoting the production of lean muscle mass. IGF-1 is a useful indicator of average GH levels. The IGF-1 test is therefore often used to help evaluate for GH deficiency or GH excess. IGF-1 deficiencies are seen early in life and are usually the result of GH deficiency. They can inhibit bone growth and overall development and can result in a child with a shorter than normal stature. In adults, decreased production can lead to low bone density, less muscle mass, and altered lipid levels. Insulin-like growth factor 1 (IGF-1) is an evolutionary conserved peptide, which has been shown to be essential in the regulation of body size, the pattern of reproductive investment and life span across a broad taxonomic range of model species in laboratory and domesticated conditions. However, studies addressing corresponding evolutionary hypotheses on a broader scale and in free-living vertebrates are very rare. This is a very useful research tool to monitor muscle development and metabolism in birds.
Format: Liquid
Storage buffer: Unpurified anti-serum from rabbit preserved in 0.02% Thiomersal
Shipping conditions: Dry ice

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