Interferons (IFNs) were originally identified as proteins that induce an antiviral state in cells, but they also have important regulatory functions in the immune system. Type I IFN (predominantly IFN-Î? and IFN-Î?) and type II IFN (IFN-Î?) play critical roles in innate and adaptive immune response against viral infection in mammals. Unlike mammals fish have two type II interferons, IFN-Î? and IFN-Î?-related (IFN-Î?rel). IFN-Î? and IFN-Î?rel have recently been shown to play a role in protecting particular species of fish against infection by pathogens such as infectious pancreatic necrosis virus (IPNV) and salmonid alphavirus 3 (SAV3). VAB4P2B4*E8 can be used…
| Inventor | Institute |
|---|---|
| Ayham Alnabulsi | Vertebrate Antibodies Limited |
| SKU: | 153451 |
|---|---|
| Product description: | Interferons (IFNs) were originally identified as proteins that induce an antiviral state in cells, but they also have important regulatory functions in the immune system. Type I IFN (predominantly IFN-ÄÂ? and IFN-ÄÂ?) and type II IFN (IFN-ÄÂ?) play critical roles in innate and adaptive immune response against viral infection in mammals. Unlike mammals fish have two type II interferons, IFN-ÄÂ? and IFN-ÄÂ?-related (IFN-ÄÂ?rel). IFN-ÄÂ? and IFN-ÄÂ?rel have recently been shown to play a role in protecting particular species of fish against infection by pathogens such as infectious pancreatic necrosis virus (IPNV) and salmonid alphavirus 3 (SAV3). VAB4P2B4*E8 can be used to study IFN-ÄÂ?rel in Atlantic salmon (Salmo salar) and Brown trout (Salmo trutta). |
| Alternate name: | IFG antibody, IFI antibody, IFN gamma antibody, IFN immune antibody, IFN-gamma antibody, IFNG antibody, Immune interferon antibody, Interferon gamma antibody |
| Conjugation: | Unconjugated |
| Isotype: | IgG |
| Molecular weight: | 22 kDa |
| Immunogen: | ovalbumin-conjugated synthetic peptide-DLKRSYYQDR; peptide immunogen is 90% identical to rainbow trout (Oncorhynchus mykiss) |
| Myeloma used: | P3X63Ag8.653 |
| Cat. #: | 153451 |
|---|---|
| Unit size: | 100 ug |
| Research Fields: | Immunology |
| Application: | ELISA ; IHC ; WB |
| Target: | Anti-IFN-ÄÂ?rel |
| Reactivity: | Salmon ; Brown Trout |
| Clone: | VAB4P2B4*E8 |
| Host: | Mouse |
| Class: | Monoclonal |
| Target background: | Interferons (IFNs) were originally identified as proteins that induce an antiviral state in cells, but they also have important regulatory functions in the immune system. Type I IFN (predominantly IFN-ÄÂ? and IFN-ÄÂ?) and type II IFN (IFN-ÄÂ?) play critical roles in innate and adaptive immune response against viral infection in mammals. Unlike mammals fish have two type II interferons, IFN-ÄÂ? and IFN-ÄÂ?-related (IFN-ÄÂ?rel). IFN-ÄÂ? and IFN-ÄÂ?rel have recently been shown to play a role in protecting particular species of fish against infection by pathogens such as infectious pancreatic necrosis virus (IPNV) and salmonid alphavirus 3 (SAV3). VAB4P2B4*E8 can be used to study IFN-ÄÂ?rel in Atlantic salmon (Salmo salar) and Brown trout (Salmo trutta). |
|---|
| Format: | Liquid |
|---|---|
| Concentration: | 0.9-1.1mg/ml |
| Storage buffer: | PBS with 0.02% azide |
| Storage conditions: | -15° C to -25° C |
| Shipping conditions: | Dry ice |
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