Anti-IFN-Gammarel [VAB4P2B4*E8]

Interferons (IFNs) were originally identified as proteins that induce an antiviral state in cells, but they also have important regulatory functions in the immune system. Type I IFN (predominantly IFN-Î? and IFN-Î?) and type II IFN (IFN-Î?) play critical roles in innate and adaptive immune response against viral infection in mammals. Unlike mammals fish have two type II interferons, IFN-Î? and IFN-Î?-related (IFN-Î?rel). IFN-Î? and IFN-Î?rel have recently been shown to play a role in protecting particular species of fish against infection by pathogens such as infectious pancreatic necrosis virus (IPNV) and salmonid alphavirus 3 (SAV3). VAB4P2B4*E8 can be used…

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