Anti-Human Ataxin-3 [4B8]

Ataxin-3 is a deubiquitinating enzyme involved in the clearance of misfolded proteins. The enzyme functions in proteasome degradation and autophagy. Mutated forms of Ataxin-3 can lead to misfolded protein aggregation which cause the neurodegenerative disorder spinocerebellar ataxia type-3 (SCA3), also known as Machado-Joseph disease.

Contributors

Inventor Institute
Patrick Loll Drexel University
SKU: 156506
Product description: Ataxin-3 is a deubiquitinating enzyme involved in the clearance of misfolded proteins. The enzyme functions in proteasome degradation and autophagy. Mutated forms of Ataxin-3 can lead to misfolded protein aggregation which cause the neurodegenerative disorder spinocerebellar ataxia type-3 (SCA3), also known as Machado-Joseph disease.
Alternate name: Machado-Joseph Disease (MJD) Protein 1; Spinocerebellar Ataxia Type 3
Conjugation: Unconjugated
Molecular weight: 42 kDa
Immunogen: Recombinant Human Ataxin-3
Immunogen Uniprot ID: ATX3_HUMAN
Cat. #: 156506
Tool sub type: Primary antibody
Unit size: 100 ug
Research Fields: Biochemistry;Neurobiology
Application: ELISA ; IP
Target: Ataxin-3
Reactivity: Human
Host: Mouse
Class: Monoclonal
Target background: Ataxin-3 is a deubiquitinating enzyme involved in the clearance of misfolded proteins. The enzyme functions in proteasome degradation and autophagy. Mutated forms of Ataxin-3 can lead to misfolded protein aggregation which cause the neurodegenerative disorder spinocerebellar ataxia type-3 (SCA3), also known as Machado-Joseph disease.
Format: Liquid
Concentration: 0.9-1.1 mg/ml
Storage buffer: PBS with 0.02% azide
Storage conditions: -15° C to -25° C
Shipping conditions: Dry ice

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