Anti-HuD [15A9] (ChIP Grade)

SKU: 153502
Product description: HuD otherwise known as ELAV-like protein 4 is a protein that in humans is encoded by the ELAVL4 gene. The HuD/ELAVL4 protein is an RNA-binding protein. HuD is expressed only in neurons and it binds to AU-rich element-containing mRNAs. As a result of this interaction the half-life of the transcript is increased. HuD is important in neurons during brain development and plasticity. Monoclonal 15A9 was generated against a unique HuD peptide and does not react with HuR, HuC, or Hel-N1. Monoclonal 15A9 works well in western blot, IHC and provides an excellent marker for neuronal cells. However, it was specifically selected becasue of its abiity to supershift HuD/mRNA ribonucleoprotein complexes. Thus, it is the ideal reagent for CHIP or RIP studies to specifically identify novel HuD targets in neuronal cells.
Alternate name: ELAV-like protein 4
Conjugation: Unconjugated
Isotype: IgG2b
Cat. #: 153502
Unit size: 100 ug
Research Fields: Developmental biology; Genetics; Neurobiology
Application: ChIP ; ELISA ; IHC ; IP ; WB
Target: HuD
Reactivity: Human
Clone: 15A9
Host: Mouse
Class: Monoclonal
Target background: HuD otherwise known as ELAV-like protein 4 is a protein that in humans is encoded by the ELAVL4 gene. The HuD/ELAVL4 protein is an RNA-binding protein. HuD is expressed only in neurons and it binds to AU-rich element-containing mRNAs. As a result of this interaction the half-life of the transcript is increased. HuD is important in neurons during brain development and plasticity. Monoclonal 15A9 was generated against a unique HuD peptide and does not react with HuR, HuC, or Hel-N1. Monoclonal 15A9 works well in western blot, IHC and provides an excellent marker for neuronal cells. However, it was specifically selected becasue of its abiity to supershift HuD/mRNA ribonucleoprotein complexes. Thus, it is the ideal reagent for CHIP or RIP studies to specifically identify novel HuD targets in neuronal cells.
Format: Liquid
Shipping conditions: Dry ice

Related Tools for Antibodies

Cat. # Tool Name
151031 Anti-RuvA [RuvA 12C6] Key Info View Tool
151026 Anti-FCGR1 [10.1] mAb Key Info View Tool
151020 Anti-CyclinB1 [V143.1] Key Info View Tool
151024 Anti-Hairy [1/24] Key Info View Tool
151027 Anti-HSVICP8 [10A3] Key Info View Tool

Tool enquiry

Please ensure you use your organisation email address rather than personal where possible, as this helps us locate your organisation in our system faster.

Please note we may take up to three days to respond to your enquiry.

CancerTools.org uses the contact information provided to respond to you about our research tools and service. For more information please review our privacy policy.