BF7 can be used for detection of HPV in cervical smears and biopsies and analysis of E6 expression in cell transformation studies.
| Inventor | Institute |
|---|---|
| Lawrence Banks | Cancer Research UK, London Research Institute: Lincoln's Inn Fields |
| SKU: | 151080 |
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| Product description: | BF7 can be used for detection of HPV in cervical smears and biopsies and analysis of E6 expression in cell transformation studies. |
| Conjugation: | Unconjugated |
| Isotype: | IgG1 |
| Molecular weight: | 16.5 kDa |
| Immunogen: | Gel-purified HPV-18 E6-b galactosidase fusion protein. |
| Myeloma used: | P3/NS1/1-Ag4.1 |
| Cat. #: | 151080 |
|---|---|
| Provenance and Ownership: | The Anti-HPV18E6 [BF7] is owned by Cancer Research UK. CancerTools supplies the Anti-HPV18E6 [BF7] under licence from Cancer Research UK and is the authorised source for its distribution. Sourcing Anti-HPV18E6 [BF7] directly from the IP owner ensures authenticity, provenance and compliance with all applicable licensing and research use requirements. |
| Tool sub type: | Primary antibody |
| Unit size: | 100 ug |
| Cancer types: | Cervical cancer |
| Research Fields: | Cancer; Microbiology |
| Application: | ELISA ; RIA ; WB |
| Target: | Human Papilloma Virus-18 early protein 6 (HPV18 E6) |
| Reactivity: | Virus |
| Clone: | BF7 |
| Host: | Mouse |
| Class: | Monoclonal |
| Target background: | BF7 can be used for detection of HPV in cervical smears and biopsies and analysis of E6 expression in cell transformation studies. |
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| Format: | Liquid |
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| Concentration: | 1 mg/ml |
| Storage buffer: | PBS with 0.02% azide |
| Storage conditions: | -15° C to -25° C |
| Shipping conditions: | Dry ice |
| References: |
Cheng et al. 2017. Mol Med Rep. 16(4):5464-5470. PMID: 28849054. Banks et al. 1987. J Gen Virol. 68 ( Pt 5):1351-9. PMID: 3033140. Identification of human papillomavirus type 18 E6 polypeptide in cells derived from human cervical carcinomas. |
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