| Inventor | Institute |
|---|---|
| Lawrence Banks | Cancer Research UK, London Research Institute: Lincoln's Inn Fields |
| SKU: | 151083 |
|---|---|
| Product description: | C1P5 can be used for detection of HPV in cervical smears and biopsies and analysis of E6 expression in cell transformation studies. |
| Conjugation: | Unconjugated |
| Isotype: | IgG1 |
| Molecular weight: | 15.8 kDa, 17 kDa |
| Immunogen: | Gel-purified HPV-18 E6-beta galactosidase fusion protein |
| Myeloma used: | P3/NS1/1-Ag4.1 |
| Cat. #: | 151083 |
|---|---|
| Provenance and Ownership: | The Anti-HPV16E6 & HPV18E6 [C1P5] is owned by Cancer Research UK. CancerTools supplies the Anti-HPV16E6 & HPV18E6 [C1P5] under licence from Cancer Research UK and is the authorised source for its distribution. Sourcing Anti-HPV16E6 & HPV18E6 [C1P5] directly from the IP owner ensures authenticity, provenance and compliance with all applicable licensing and research use requirements. |
| Tool sub type: | Primary antibody |
| Unit size: | 100 ug |
| Cancer types: | Cervical cancer |
| Research Fields: | Cancer; Microbiology |
| Application: | IHC ; IP ; WB |
| Target: | Human Papilloma Virus-16 and 18 early protein 6 (HPV16E6 & HPV18 E6) |
| Reactivity: | Human papilloma virus |
| Clone: | C1P5 |
| Host: | Mouse |
| Class: | Monoclonal |
| Target background: | The human papilloma virus (HPV) family of DNA tumor viruses includes HPV-16 and HPV-18, which are associated with a large proportion of cervical cancer cases. HPV early proteins E6 and E7 are the major viral oncoproteins that regulate cell proliferation through the inactivation of p53 and Rb1 tumour suppressor proteins respectively. |
|---|
| Format: | Liquid |
|---|---|
| Concentration: | 0.81 mg/ml |
| Storage buffer: | PBS with 0.02% azide |
| Storage conditions: | ‘-15° C to -25° C |
| Shipping conditions: | Dry ice |
| References: |
Xie et al. 2014. Oncogene. 33(8):1037-46. PMID: 23474763. Herfs et al. 2012. Proc Natl Acad Sci U S A. 109(26):10516-21. PMID: 22689991. Lawson et al. 2009. Br J Cancer. 101(8):1351-6. PMID: 19773762. Zhang et al. 2005. J Biol Chem. 280(39):33165-77. PMID: 15983032. Banks et al. 1987. J Gen Virol. 68 ( Pt 5):1351-9. PMID: 3033140. |
|---|
| Cat. # | Tool Name | |||||||||||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 151017 | null |
Key Info
null
|
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| 151034 | Anti-HSVUL42 [13D11] |
Key Info
Anti-HSVUL42 [13D11]
|
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| 151036 | Anti-ICAM1 [15.2] |
Key Info
Anti-ICAM1 [15.2]
|
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| 151039 | Anti-Integrin aVb3 [23C6] |
Key Info
Anti-Integrin aVb3 [23C6]
|
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| 151040 | Anti-Integrins aL, aX, aMb2 [24] |
Key Info
Anti-Integrins aL, aX, aMb2 [24]
|
View Tool | |||||||||||||||||||
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