Anti-HLADRa [TAL 1B5]

TAL 1B5 may be used for HLA typing.

Contributors

Institute
Cancer Research UK, London Research Institute: Lincoln's Inn Fields
Cat. #: 151227
Tool sub type: Primary antibody
Unit size: 100 ug
Research Fields: Immunology
Application: IHC ; ELISA ; FACS ; IHC ; IF ; RIA ; WB
Target: Human Leukocyte Antigen DR, alpha subunit
Reactivity: Human
Clone: TAL 1B5
Host: Mouse
Class: Monoclonal
Product description: TAL 1B5 may be used for HLA typing.
Conjugation: Unconjugated
Isotype: IgG1
Molecular weight: 33 kDa
Immunogen: Bristol 8 separated alpha chain preparation
Myeloma used: P3/NS1/1-Ag4.1
Target background: Human Leukocyte Antigens are highly polymorphic proteins that are involved in the presentation of antigens to the T-cell receptor. There are two classes of HLA antigens, class I (HLA-A, HLA-B and HLA-C) and class II (HLA-D).
Format: Liquid
Concentration: 1 mg/ml
Storage buffer: PBS with 0.02% azide
Storage conditions: -15° C to -25° C
Shipping conditions: Dry ice
References:

Roher et al. 2013. PLoS One. 8(3):e59735. PMID: 23555764.

Bapineuzumab alters a? composition: implications for the amyloid cascade hypothesis and anti-amyloid immunotherapy.

Chung et al. 2012. Int J Cancer. 131(3):E227-35. PMID: 22174092.

Tumor-associated macrophages correlate with response to epidermal growth factor receptor-tyrosine kinase inhibitors in advanced non-small cell lung cancer.

van Dongen et al. 2010. Int J Cancer. 127(4):899-909. PMID: 20013807.

Anti-inflammatory M2 type macrophages characterize metastasized and tyrosine kinase inhibitor-treated gastrointestinal stromal tumors.

Thomas et al. 1988. J Pathol. 154(4):353-63. PMID: 2455029.

HLA-D region alpha-chain monoclonal antibodies: cross-reaction between an anti-DP alpha-chain antibody and smooth muscle.

Adams et al. 1983. Immunology. 50(4):613-24. PMID: 6197354.

Production and characterization of monoclonal antibodies recognizing the alpha-chain subunits of human ia alloantigens.

Images

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Adapted from Roher et al. 2013. PLoS One. 8(3)

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