Anti-HLA-G [87G]

MoAb recognizes both HLA-G1 and the solube HLA-G5.

Contributors

Inventor Institute
Daniel Geraghty Fred Hutchinson Cancer Center
SKU: 161666
Product description: MoAb recognizes both HLA-G1 and the solube HLA-G5.
Isotype: IgG2a,?
Molecular weight: The heavy chain is approximately 45 kDa
Cat. #: 161666
Tool sub type: Primary antibody
Cancer types: Skin cancer;Breast cancer
Research Fields: Developmental biology;Immunology
Application: FACS, IP(weak), ELISA, Histology. No western
Target: HLA-G
Reactivity: Human
Clone: 87G
Host: Mouse
Class: Monoclonal
Primary citation: lshitani et al.2003. Journal of lmmunology. 171(3):1376-84. PMID: 12874228
Target background: HLA-G are expressed in the placenta, a membrane form and a soluble form, the latter containing an altered carboxyl terminu. HLA-G belongs to the HLA class I heavy chain paralogues. This class I molecule is a heterodimer consisting of a heavy chain and a light chain (?2 microglobulin). The heavy chain is anchored in the membrane.
Storage buffer: PBS, pH 7.2
Storage conditions: 4° C
Shipping conditions: Dry ice
References:

lshitani et al.2003.Journal of lmmunology. 171(3):1376-84.PMID: 12874228

Lee et al.1995. Immunity.(5):591-600.PMID: 7584149

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