Heterogeneous nuclear ribonucleoproteins (hnRNPs) are a family of ubiquituous expressed proteins that bind directly to nascent RNA Polymerase II transcripts and play a role in packaging and alternative splicing of pre-mRNAs, as well mRNA transport and metabolism.
| Inventor | Institute |
|---|---|
| Maurice Swanson | University of Florida Research Foundation |
| Cat. #: | 158402 |
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| Tool sub type: | Primary antibody |
| Unit size: | 100 ug |
| Research Fields: | Cell signaling and signal transduction;Genetics |
| Application: | WB ; IHC ; IF ; IP |
| Target: | Heterogeneous nuclear ribonucleoprotein M 1-4 |
| Reactivity: | Human |
| Host: | Mouse |
| Class: | Monoclonal |
| Alternate name: | HNRNPM, hnRNP |
|---|---|
| Product description: | Heterogeneous nuclear ribonucleoproteins (hnRNPs) are a family of ubiquituous expressed proteins that bind directly to nascent RNA Polymerase II transcripts and play a role in packaging and alternative splicing of pre-mRNAs, as well mRNA transport and metabolism. The M proteins are pre-mRNA binding proteins in vivo, and bind to poly(G) and poly(U) RNA homopolymers in vitro. the M4 is the largest M protein. |
| Conjugation: | Unconjugated |
| Isotype: | IgG2b |
| Immunogen: | Recombinant fusion protein of the entire human M protein |
| Target background: | Heterogeneous nuclear ribonucleoproteins (hnRNPs) are a family of ubiquituous expressed proteins that bind directly to nascent RNA Polymerase II transcripts and play a role in packaging and alternative splicing of pre-mRNAs, as well mRNA transport and metabolism. The M proteins are pre-mRNA binding proteins in vivo, and bind to poly(G) and poly(U) RNA homopolymers in vitro. the M4 is the largest M protein. |
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| Format: | Liquid |
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| Shipping conditions: | Dry ice |
| References: |
Datar et al. 1993. Nucleic Acids Res. 21(3):439-46. PMID: 8441656. |
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