Monoclonal antibody with a broad spectrum of inhibitory effects on the expansion of T cells induced via TCR.
| Institute |
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| Yale University |
| SKU: | 155239 |
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| Product description: | Monoclonal antibody with a broad spectrum of inhibitory effects on the expansion of T cells induced via TCR. Background and Research Application Signal transducer CD24 also known as cluster of differentiation 24 or heat stable antigen CD24 (HSA) is a cell adhesion molecule encoded by the CD24 gene. Anti-HSA significantly inhibits the proliferation of CD4 T cells induced by anti-CD3 or by allogeneic LPS-activated B cells. Engagement of the TCR in the presence of this monoclonal antibody leads… |
| Conjugation: | Unconjugated |
| Immunogen: | P07900 |
| Immunogen Uniprot ID: | P07900 |
| Cat. #: | 155239 |
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| Tool sub type: | Primary antibody |
| Unit size: | 100 ug |
| Research Fields: | Immunology |
| Target: | Heat Stable Antigen |
| Class: | Monoclonal |
| Target background: | Monoclonal antibody with a broad spectrum of inhibitory effects on the expansion of T cells induced via TCR. Background and Research Application Signal transducer CD24 also known as cluster of differentiation 24 or heat stable antigen CD24 (HSA) is a cell adhesion molecule encoded by the CD24 gene. Anti-HSA significantly inhibits the proliferation of CD4 T cells induced by anti-CD3 or by allogeneic LPS-activated B cells. Engagement of the TCR in the presence of this monoclonal antibody le… |
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| Format: | Liquid |
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| Concentration: | 1 mg/ml |
| Storage buffer: | PBS with 0.02% azide |
| Storage conditions: | Store at -20° C frozen. Avoid repeated freeze / thaw cycles |
| Shipping conditions: | Dry ice |
| References: |
Li et al. 2006. J Exp Med. 203(7):1713-20. PMID: 16769998. Bai et al. 2004. J Exp Med. 200(4):447-58. PMID: 15314074. Liu et al. 1992. J Exp Med. 175(2):437-45. PMID: 1346270. |
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