Anti-HA (H1N1) [LM41]

Contributors

Inventor Institute
Nigel Dimmock University of Warwick
SKU: 153417
Product description: The hemagglutinin (HA) protein is one of two major surface glycoproteins on the envelope of influenza A virus. The HA protein is responsible for receptor binding to host cells and for viral entry and is therefore the primary target of neutralizing antibodies. LM41 recognises an epitope of the A/WSN (H1N1) HA antigen only when expressed in H-2k cells. LM41 inhibited Ag-specific, MHC class I-restricted lysis of H-2k target cells infected with a vaccinia recombinant virus expressing the HA of A/WSN by CTL from A/WSN virus-infected H-2k mice.
Alternate name: Hemagglutinin Antibody, Anti-HA, HA, Antibody, Anti-Influenza A, Anti-H1N1 HA, Influenza A Antibody, Flu Antibody, AWSN Antibody, H1N1 Antibody, Anti-AWSN, A/WSN Antibody, Anti-A/WSN
Conjugation: Unconjugated
Isotype: IgM
Immunogen: C3WHe-mg (H-2k) mice were infected with A/WSN (H1N1)
Myeloma used: Sp2/0-Ag14
Cat. #: 153417
Unit size: 100 ug
Research Fields: Immunology; Microbiology
Application: ELISA ; Fn
Target: A/WSN (H1N1) hemagglutinin
Reactivity: Virus
Clone: LM41
Host: Mouse
Class: Monoclonal
Target background: The hemagglutinin (HA) protein is one of two major surface glycoproteins on the envelope of influenza A virus. The HA protein is responsible for receptor binding to host cells and for viral entry and is therefore the primary target of neutralizing antibodies. LM41 recognises an epitope of the A/WSN (H1N1) HA antigen only when expressed in H-2k cells. LM41 inhibited Ag-specific, MHC class I-restricted lysis of H-2k target cells infected with a vaccinia recombinant virus expressing the HA of A/WSN by CTL from A/WSN virus-infected H-2k mice.
Format: Liquid
Shipping conditions: Dry ice
References:

McLain et al. 1993. J Immunol. 150(8 Pt 1):3421-6. PMID: 7682240.

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