Anti-Germinal Centre macrophages [BU83]

Macrophages are a type of white blood cell which through a process called phagocytosis engulfs and digests cellular debris, foreign substances, microbes, cancer cells.

Contributors

Inventor Institute
Margaret Goodall University of Birmingham
SKU: 153227
Product description: Macrophages are a type of white blood cell which through a process called phagocytosis engulfs and digests cellular debris, foreign substances, microbes, cancer cells. They can be found in all tissues where they play a critical role in the innate immune system and also help initiate adaptive immunity through recruiting lymphocytes and other immune cells. Germinal centres are sites within secondary lymph nodes where mature B lymphocytes proliferate, differentiate and mutate their antibody genes, enabling switching of their class of antibody during the course of infection.
Alternate name: PB33
Conjugation: Unconjugated
Isotype: IgG2a
Immunogen: Pre-B cells
Cat. #: 153227
Tool sub type: Primary antibody
Unit size: 100 ug
Research Fields: Immunology
Application: IHC
Target: Macrophages
Reactivity: Human
Clone: BU83
Host: Mouse
Class: Monoclonal
Target background: Macrophages are a type of white blood cell which through a process called phagocytosis engulfs and digests cellular debris, foreign substances, microbes, cancer cells. They can be found in all tissues where they play a critical role in the innate immune system and also help initiate adaptive immunity through recruiting lymphocytes and other immune cells. Germinal centres are sites within secondary lymph nodes where mature B lymphocytes proliferate, differentiate and mutate their antibody genes, enabling switching of their class of antibody during the course of infection.
Format: Liquid
Concentration: 0.9-1.1 mg/ml
Storage buffer: PBS with 0.02% azide
Storage conditions: -15° C to -25° C
Shipping conditions: Dry ice

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