Anti-FOXP1 [JC12]
JC12 has been used in the identification of a novel winged helix transcription factor, FOXP1.
Contributors
| Inventor | Institute |
|---|---|
| Alison Banham | University of Oxford |
| SKU: | 151896 |
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| Product description: | JC12 has been used in the identification of a novel winged helix transcription factor, FOXP1. |
| Conjugation: | Unconjugated |
| Isotype: | IgG2a |
| Cat. #: | 151896 |
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| Tool sub type: | Primary antibody |
| Unit size: | 100 ug |
| Application: | WB ; ChIP ; IHC |
| Target: | FOXP1 |
| Reactivity: | Mouse |
| Clone: | JC12 |
| Host: | Mouse |
| Class: | Monoclonal |
| Target background: | The FOXP1 gene has been mapped to chromosome 3p14.1, a chromosomal locus shown to be disrupted in a range of solid tumors. Characterization of both FOXP1 mRNA and protein expression has shown that this molecule is widely expressed in normal tissues, and that its expression is frequently altered in solid tumors. |
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| Format: | Liquid |
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| Concentration: | 1mg/ml |
| Storage buffer: | PBS with 0.02% azide |
| Storage conditions: | ‘-15° C to -25° C |
| Shipping conditions: | Dry ice |
| References: |
Vitamin D Receptor Expression in Plasmablastic Lymphoma and Myeloma Cells Confers Susceptibility to Vitamin D. Gascoyne et al. 2016. Endocrinology. :en20161802. PMID: 28001444. Gascoyne et al. 2016. Leuk Lymphoma. :1-15. PMID: 27678023. The significance of FOXP1 in diffuse large B-cell lymphoma. FOXP2-positive diffuse large B-cell lymphomas exhibit a poor response to R-CHOP therapy and distinct biological signatures. Wong et al. 2016. Oncotarget. :. PMID: 27224915. Brown et al. 2… |
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