Anti-Follistatin 315 [H10]

Clone H10 recognizes an epitope on the C-terminal region of human Follistatin 315, allowing for detection of FSH levels using various analysis methods. ELISA experiments showed that H10 interacts with FS315 and does not interact with FS288.

Contributors

Institute
BioServ UK Ltd
SKU: 153635
Product description: Follistatin is a single-chain glycosylated protein that inhibits follicle stimulating hormone (FSH) release. Alternative splicing of Follistatin mRNA yields two isoforms, FS315 and FS288. FS315 is considered the main circulating form of Follistatin. Clone H10 recognizes an epitope on the C-terminal region of human Follistatin 315, allowing for detection of FSH levels using various analysis methods. ELISA experiments showed that H10 interacts with FS315 and does not interact with FS288.
Alternate name: Follistatin, FS, FST, Active-binding protein
Conjugation: Unconjugated
Isotype: IgG2a
Molecular weight: 37 kDa
Immunogen: Synthetic peptide corresponding to sequence CDEDQDYSFPISSILEW of the C- terminal region of human Follistatin 315
Myeloma used: Sp2/0-Ag14
Cat. #: 153635
Tool sub type: Primary antibody
Unit size: 100 ug
Research Fields: Cancer; Cell signaling and signal transduction; Genetics; Immunology; Neurobiology; Stem cell biology
Application: ELISA ; IHC ; WB
Target: Follistatin 315
Reactivity: Human
Clone: H10
Host: Mouse
Class: Monoclonal
Target background: Follistatin is a single-chain glycosylated protein that inhibits follicle stimulating hormone (FSH) release. Alternative splicing of Follistatin mRNA yields two isoforms, FS315 and FS288. FS315 is considered the main circulating form of Follistatin. Clone H10 recognizes an epitope on the C-terminal region of human Follistatin 315, allowing for detection of FSH levels using various analysis methods. ELISA experiments showed that H10 interacts with FS315 and does not interact with FS288.
Format: Liquid
Shipping conditions: Dry ice
References:

Fitzgerald et al. 2012. Invest Ophthalmol Vis Sci. 53(11):7358-69. PMID: 23010638.

The effects of transforming growth factor-?2 on the expression of follistatin and activin A in normal and glaucomatous human trabecular meshwork cells and tissues.

Pratic et al. 2004. Chem Phys Lipids. 128(1-2):165-71. PMID: 15037161.

F2-isoprostanes as indices of lipid peroxidation in inflammatory diseases.

Cancilla et al. 2001. Dev Biol. 237(1):145-58. PMID: 11518512.

Regulation of prostate branching morphogenesis by activin A and follistatin.

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