Follicular dendritic cells (FDC), described as embryonal non-phagocytic reticulum cells are found exclusively in B cell-rich follicles of peripheral lymphoid tissue. In the germinal centres of secondary follicles their cytoplasmic processes form a dense network closely associated with the lymphoid cells.
| Institute |
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| University of Birmingham |
| SKU: | 151453 |
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| Product description: | Follicular dendritic cells (FDC), described as embryonal non-phagocytic reticulum cells are found exclusively in B cell-rich follicles of peripheral lymphoid tissue. In the germinal centres of secondary follicles their cytoplasmic processes form a dense network closely associated with the lymphoid cells. |
| Conjugation: | Unconjugated |
| Isotype: | IgM |
| Cat. #: | 151453 |
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| Unit size: | 100 ug |
| Research Fields: | Immunology |
| Application: | FACS ; IHC |
| Target: | Follicular dendritic cell marker |
| Reactivity: | Human |
| Clone: | BU57 |
| Host: | Mouse |
| Class: | Monoclonal |
| Target background: | Follicular dendritic cells (FDC), described as embryonal non-phagocytic reticulum cells are found exclusively in B cell-rich follicles of peripheral lymphoid tissue. In the germinal centres of secondary follicles their cytoplasmic processes form a dense network closely associated with the lymphoid cells. |
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| Format: | Liquid |
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| Concentration: | 0.9-1.1mg/ml |
| Storage buffer: | PBS with 0.02% azide |
| Storage conditions: | -15° C to -25° C |
| Shipping conditions: | Dry ice |
| References: |
Maeda K et al. Dendrtic Cells. 1996. 6: 43-9 Maeda et al. 2002. J Histochem Cytochem. 50(11):1475-86. PMID: 12417613. Immunohistochemical recognition of human follicular dendritic cells (FDCs) in routinely processed paraffin sections. Ling et al. 1998. Clin Exp Immunol. 113(3):360-6. PMID: 9737663. Origin and properties of soluble CD21 (CR2) in human blood. Johnson et al. 1986. Clin Exp Immunol. 64(1):205-13. PMID: 3524917. Human follicular dendritic cells (FDC): a study with monoclonal antibodies (MoAb). |
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