Anti-Fibrinogen-like Protein 1 [177 m01]

FLG-1 ablation in mice promotes T cell immunity. FLG1 is shown to be highly produced in cancer cells.

Contributors

Inventor Institute
Leiping Chen Yale University
SKU: 159684
Product description: Fibrinogen-like Protein 1 (FLG-1) is secreted liver protein and inhibits antigen-specific T cell activation. FLG-1 binds to lymphocyte-activation gene 3 (LAG3), independent from MHC-Class II. FLG-1 ablation in mice promotes T cell immunity. FLG1 is shown to be highly produced in cancer cells.
Alternate name: FGL-1
Conjugation: Unconjugated
Isotype: IgG1 kappa
Cat. #: 159684
Tool sub type: Primary antibody
Unit size: 100 ug
Research Fields: Immunology
Application: ELISA
Target: Fibrinogen-like Protein 1
Reactivity: Human
Host: Mouse
Class: Monoclonal
Target background: Fibrinogen-like Protein 1 (FLG-1) is secreted liver protein and inhibits antigen-specific T cell activation. FLG-1 binds to lymphocyte-activation gene 3 (LAG3), independent from MHC-Class II. FLG-1 ablation in mice promotes T cell immunity. FLG1 is shown to be highly produced in cancer cells.
Format: Liquid
Concentration: 1 mg/ml
Storage buffer: PBS with 0.02% azide
Storage conditions: -15° C to -25° C
Shipping conditions: Dry ice
References:

Wang et al. 2019. Cell. 176(1-2):334-347.e12. PMID: 30580966.

Tool enquiry

Please ensure you use your organisation email address rather than personal where possible, as this helps us locate your organisation in our system faster.

Please note we may take up to three days to respond to your enquiry.

CancerTools.org uses the contact information provided to respond to you about our research tools and service. For more information please review our privacy policy.