A mouse monoclonal antibody recognising human fibrin alpha chain, used to study fibrin formation, clot structure and haemostatic processes.
| Inventor | Institute |
|---|---|
| Nancy Hogg | Cancer Research UK, London Research Institute: Lincoln's Inn Fields |
| SKU: | 151172 |
|---|---|
| Product description: | Anti-Fibrin [UC45] is a mouse monoclonal antibody that recognises the human fibrin alpha chain. It is used to detect and study fibrin, supporting research into fibrin formation, clot structure and haemostatic processes. Reported applications include immunofluorescence, FACS, immunoprecipitation and radioimmunoassay. |
| Conjugation: | Unconjugated |
| Isotype: | IgM |
| Molecular weight: | 45 kDa |
| Immunogen: | Human acute monoblastic leukemia cells. |
| Myeloma used: | P3/NS1/1-Ag4.1 |
| Cat. #: | 151172 |
|---|---|
| Tool sub type: | Primary antibody |
| Unit size: | 100 ug |
| Research Fields: | Tissue-specific biology |
| Application: | IF ; FACS ; IF ; IP ; RIA |
| Target: | Fibrin alpha chain |
| Reactivity: | Human |
| Clone: | UC45 |
| Host: | Mouse |
| Class: | Monoclonal |
| Target background: | Fibrin (also called Factor Ia) is a fibrous protein involved in the clotting of blood, and is non-globular. It is a fibrillar protein that is polymerised to form a “mesh” that forms a hemostatic plug or clot (in conjunction with platelets) over a wound site. |
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| Format: | Liquid |
|---|---|
| Concentration: | 1 mg/ml |
| Storage buffer: | PBS with 0.02% azide |
| Storage conditions: | -15° C to -25° C |
| Shipping conditions: | Dry ice |
| References: |
Wu et al. 2013. Am J Nucl Med Mol Imaging. 3(5):446-55. PMID: 24116353. Linch et al. 1984. Blood. 63(3):566-73. PMID: 6365201. Hogg et al. 1983. J Exp Med. 157(2):473-85. PMID: 6822786. Hogg et al. 1981. Cell. 24(3):875-84. PMID: 6788378. |
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