FANCM is part of the Fanconi Anemia core complex of proteins. The Fanconi anemia pathway is implicated in DNA repair and cancer predisposition.
| Inventor | Institute |
|---|---|
| Stephen West | Cancer Research UK, London Research Institute: Clare Hall Laboratories |
| SKU: | 151615 |
|---|---|
| Product description: | FANCM is part of the Fanconi Anemia core complex of proteins. The Fanconi anemia pathway is implicated in DNA repair and cancer predisposition. |
| Conjugation: | Unconjugated |
| Immunogen: | Recombinant 6 HIS tagged human FANCM fragment expressed in E. coli |
| Cat. #: | 151615 |
|---|---|
| Provenance and Ownership: | The Anti-FANCM [SWE98] is owned by Cancer Research UK. CancerTools supplies the Anti-FANCM [SWE98] under licence from Cancer Research UK and is the authorised source for its distribution. Sourcing Anti-FANCM [SWE98] directly from the IP owner ensures authenticity, provenance and compliance with all applicable licensing and research use requirements. |
| Tool sub type: | Primary antibody |
| Unit size: | 100 ug |
| Research Fields: | Genetics |
| Application: | IF ; IP ; WB |
| Target: | Fanconi anemia, complementation group M protein alpha (aFANCM) |
| Reactivity: | Human |
| Clone: | SWE98 |
| Host: | Rabbit |
| Class: | Polyclonal |
| Target background: | FANCM is part of the Fanconi Anemia core complex of proteins. The Fanconi anemia pathway is implicated in DNA repair and cancer predisposition. |
|---|
| Format: | Liquid |
|---|---|
| Concentration: | 0.9-1.1 mg/ml |
| Storage buffer: | Serum |
| Storage conditions: | -15° C to -25° C |
| Shipping conditions: | Dry ice |
| References: |
Ciccia et al. 2007. Mol Cell. 25(3):331-43. PMID: 17289582. Identification of FAAP24, a Fanconi anemia core complex protein that interacts with FANCM. |
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