Anti-Elafin

Some anti-elastase activity is found in cultured keratinocytes and in epidermis from psoriasis patients, but not in normal human epidermis. This inhibitory effect has been shown to be mediated by SKALP, Skin-derived antileukoproteinase also known as Elafin.

Contributors

Inventor Institute
Gijs Johannes de Jongh Radboud University Medical Center
SKU: 160399
Product description: Some anti-elastase activity is found in cultured keratinocytes and in epidermis from psoriasis patients, but not in normal human epidermis. This inhibitory effect has been shown to be mediated by SKALP, Skin-derived antileukoproteinase also known as Elafin.
Alternate name: Elastase-specific inhibitor (ESI), Peptidase inhibitor 3 (PI-3), Protease inhibitor WAP3,Skin-derived antileukoproteinase (SKALP), WAP four-disulfide core domain protein 14
Conjugation: Unconjugated
Molecular weight: 18kDa
Immunogen: P19957
Immunogen Uniprot ID: P19957
Cat. #: 160399
Unit size: 100 ug
Research Fields: Tissue-specific biology
Application: Fn
Target: Elafin; SKALP
Host: Rabbit
Class: Polyclonal
Target background: Some anti-elastase activity is found in cultured keratinocytes and in epidermis from psoriasis patients, but not in normal human epidermis. This inhibitory effect has been shown to be mediated by SKALP, Skin-derived antileukoproteinase also known as Elafin.
Format: Liquid
Shipping conditions: Dry ice
References:

Schalkwijk et al. 1991. Biochim Biophys Acta. 1096(2):148-54. PMID: 2001428.

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