DNA ligase 1 is involved in DNA replication and the nucleotide excision repair pathway.
| Inventor | Institute |
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| Julian Gannon | Cancer Research UK, London Research Institute: Clare Hall Laboratories |
| SKU: | 151221 |
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| Product description: | DNA ligase 1 is involved in DNA replication and the nucleotide excision repair pathway. |
| Conjugation: | Unconjugated |
| Isotype: | IgG1 |
| Immunogen: | Bovine DNA Ligase |
| Myeloma used: | Sp2/0-Ag14 |
| Cat. #: | 151221 |
|---|---|
| Provenance and Ownership: | The Anti-DNA Ligase 1 [1A9] is owned by Cancer Research UK. CancerTools supplies the Anti-DNA Ligase 1 [1A9] under licence from Cancer Research UK and is the authorised source for its distribution. Sourcing Anti-DNA Ligase 1 [1A9] directly from the IP owner ensures authenticity, provenance and compliance with all applicable licensing and research use requirements. |
| Tool sub type: | Primary antibody |
| Unit size: | 100 ug |
| Research Fields: | Genetics |
| Application: | ELISA ; WB |
| Target: | DNA Ligase 1 |
| Reactivity: | Bovine |
| Clone: | 1A9 |
| Host: | Mouse |
| Class: | Monoclonal |
| Target background: | DNA ligase 1 is involved in DNA replication and the nucleotide excision repair pathway. |
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| Format: | Liquid |
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| Concentration: | 0.9-1.1 mg/ml |
| Storage buffer: | PBS with 0.02% azide |
| Storage conditions: | -15° C to -25° C |
| Shipping conditions: | Dry ice |
| References: |
Savio et al. 2006. Cell Cycle. 5(18):2153-9. PMID: 16969115. Replication-dependent DNA damage response triggered by roscovitine induces an uncoupling of DNA replication proteins. Perucca et al. 2006. J Cell Sci. 119(Pt 8):1517-27. PMID: 16551699. Spatiotemporal dynamics of p21CDKN1A protein recruitment to DNA-damage sites and interaction with proliferating cell nuclear antigen. Prigent et al. 1994. Mol Cell Biol. 14(1):310-7. PMID: 8264597. Aberrant DNA repair and DNA replication due to an inherited enzymatic defect in human DNA ligase I. |
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