Anti-DJ-1 [E2-1A]

DJ-1 is a broadly conserved protein among both prokaryotic and eukaryotic cells. It has been identified as playing a diverse role in a range of cellular processes.

Contributors

Inventor Institute
Yaacov Hod Stony Brook University
Cat. #: 160671
Tool sub type: Primary antibody
Unit size: 100 ug
Research Fields: Apoptosis and autophagy;Cancer;Neurobiology
Application: IHC ; WB
Target: DJ-1
Reactivity: Human
Host: Mouse
Class: Monoclonal
Alternate name: PARK7
Product description: DJ-1 is a broadly conserved protein among both prokaryotic and eukaryotic cells. It has been identified as playing a diverse role in a range of cellular processes. DJ-1 was originally proposed to be a pro-oncogene, and has since been shown to be expressed at varying levels in breast, non-small cell lung and prostate cancer. It has been demonstrated to paly a role in the regulation of RNA-binding proteins as well as the regulation of testicular androgen receptors and fertilization. In addition, mutations in DJ-1 have been linked to autosomal recessive early-onset familial Parkinson's disease, and have been shown to be a key component of the oxidative stress and ubiquitin-proteasome system response (see Hod, 2004 PMID: 15258905 for additional details).
Conjugation: Unconjugated
Isotype: IgM
Molecular weight: 24 kDa
Immunogen: Full length recombinant human DJ-1
Target background: DJ-1 is a broadly conserved protein among both prokaryotic and eukaryotic cells. It has been identified as playing a diverse role in a range of cellular processes. DJ-1 was originally proposed to be a pro-oncogene, and has since been shown to be expressed at varying levels in breast, non-small cell lung and prostate cancer. It has been demonstrated to paly a role in the regulation of RNA-binding proteins as well as the regulation of testicular androgen receptors and fertilization. In addition, mutations in DJ-1 have been linked to autosomal recessive early-onset familial Parkinson's disease, and have been shown to be a key component of the oxidative stress and ubiquitin-proteasome system response (see Hod, 2004 PMID: 15258905 for additional details).
Format: Liquid
Shipping conditions: Dry ice
References:

Hod et al. 2004. J Cell Biochem. 92(6):1221-33. PMID: 15258905.

Hod et al. 1999. J Cell Biochem. 72(3):435-44. PMID: 10022524.

Related Tools for Antibodies

Cat. # Tool Name
151030 Anti-Progesterone [11P14] Key Info View Tool
151016 Anti-CyclinA [E72.1] Key Info View Tool
151031 Anti-RuvA [RuvA 12C6] Key Info View Tool
151037 Anti-Cdk1 [17 (A17)] Key Info View Tool
151039 Anti-Integrin aVb3 [23C6] Key Info View Tool

Tool enquiry

Please ensure you use your organisation email address rather than personal where possible, as this helps us locate your organisation in our system faster.

Please note we may take up to three days to respond to your enquiry.

CancerTools.org uses the contact information provided to respond to you about our research tools and service. For more information please review our privacy policy.