| Inventor | Institute |
|---|---|
| Ahmad Waseem | Queen Mary University of London |
| SKU: | 153494 |
|---|---|
| Product description: | The cytoskeleton in keratinocytes is a complex of highly homologous structural proteins derived from two families of type I and type II polypeptides. Keratin K2e is a type II polypeptide that is expressed in epidermis late in differentiation. K2e expression in skin is sensitive to keratinocyte activation but its up-regulation in oral lesions is a reflection of the degree of orthokeratinization. |
| Alternate name: | CK 2e antibody, Cytokeratin-2e antibody, Epithelial keratin-2e antibody, K2e antibody, Keratin type II cytoskeletal 2 epidermal antibody, Keratin-2 epidermis antibody, KRT2 antibody, KRT2A antibody, KRT2E antibody, Type-II keratin Kb2 antibody |
| Conjugation: | Unconjugated |
| Isotype: | IgM |
| Immunogen: | C terminus of the K2e polypeptide (synthetic peptide NH2-GEAFGSSVTFSFR-COOH) |
| Myeloma used: | Sp2/0-Ag14 |
| Cat. #: | 153494 |
|---|---|
| Provenance and Ownership: | The Anti-Cytokeratin 2e [LHK2E] is owned by Cancer Research UK. CancerTools supplies the Anti-Cytokeratin 2e [LHK2E] under licence from Cancer Research UK and is the authorised source for its distribution. Sourcing Anti-Cytokeratin 2e [LHK2E] directly from the IP owner ensures authenticity, provenance and compliance with all applicable licensing and research use requirements. |
| Tool sub type: | Primary antibody |
| Unit size: | 100 ug |
| Research Fields: | Cancer; Cell signaling and signal transduction |
| Application: | IHC ; WB |
| Target: | Keratin K2e |
| Reactivity: | Human |
| Clone: | LHK2E |
| Host: | Mouse |
| Class: | Monoclonal |
| Target background: | The cytoskeleton in keratinocytes is a complex of highly homologous structural proteins derived from two families of type I and type II polypeptides. Keratin K2e is a type II polypeptide that is expressed in epidermis late in differentiation. K2e expression in skin is sensitive to keratinocyte activation but its up-regulation in oral lesions is a reflection of the degree of orthokeratinization. |
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| Format: | Liquid |
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| Shipping conditions: | Dry ice |
| References: |
Bloor et al. 2003. Am J Pathol. 162(3):963-75. PMID: 12598329. Expression of keratin K2e in cutaneous and oral lesions: association with keratinocyte activation, proliferation, and keratinization. |
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