Cytokeratin-10 is a member of the type I (acidic) cytokeratin family, which belongs to the superfamily of intermediate filament (IF) proteins. Keratins are hetero-polymeric structural proteins which form the intermediate filament. These filaments, along with actin microfilaments and microtubules, compose the cytoskeleton of epithelial cells. Mutations in this gene are associated with epidermolytic hyperkeratosis
| Inventor | Institute |
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| Arnoud Sonnenberg | Netherlands Cancer Institute |
| SKU: | 154736 |
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| Product description: | Cytokeratin-10 is a member of the type I (acidic) cytokeratin family, which belongs to the superfamily of intermediate filament (IF) proteins. Keratins are hetero-polymeric structural proteins which form the intermediate filament. These filaments, along with actin microfilaments and microtubules, compose the cytoskeleton of epithelial cells. Mutations in this gene are associated with epidermolytic hyperkeratosis |
| Alternate name: | KRT1; Keratin 1 |
| Conjugation: | Unconjugated |
| Isotype: | IgG1 |
| Molecular weight: | 59 kDa |
| Immunogen: | Cytoskeletal preperation extracted from humen epidermis |
| Myeloma used: | Sp2/0-Ag14 |
| Cat. #: | 154736 |
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| Tool sub type: | Primary antibody |
| Unit size: | 100 ug |
| Research Fields: | Cancer; Cell biology |
| Application: | FACS ; WB |
| Target: | Cytokeratin 10 |
| Reactivity: | Dog ; Human ; Feline |
| Host: | Mouse |
| Class: | Monoclonal |
| Target background: | Cytokeratin-10 is a member of the type I (acidic) cytokeratin family, which belongs to the superfamily of intermediate filament (IF) proteins. Keratins are hetero-polymeric structural proteins which form the intermediate filament. These filaments, along with actin microfilaments and microtubules, compose the cytoskeleton of epithelial cells. Mutations in this gene are associated with epidermolytic hyperkeratosis |
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| Format: | Liquid |
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| Concentration: | 0.9-1.1 mg/ml |
| Storage buffer: | PBS with 0.02% azide |
| Storage conditions: | -15° C to -25° C |
| Shipping conditions: | Dry ice |
| References: |
van der Velden et al. 1993. Head Neck. 15(2):133-46. PMID: 7680025. Ivanyi et al. 1989. J Pathol. 159(1):7-12. PMID: 2478685. |
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