Anti-CUL-4A

CUL-4A has been implicated in several cancers and the pathogenesis of certain viruses including HIV.

Contributors

Institute
University of Illinois Chicago
SKU: 156385
Product description: CUL-4A regulates numerous key processes such as DNA repair, chromatin remodeling, spermatogenesis, haematopoiesis and the mitotic cell cycle. Moreover, CUL-4A is a core component of multiple cullin-RING-based E3 ubiquitin-protein ligase complexes which mediate the ubiquitination of target proteins. As a result, CUL-4A has been implicated in several cancers and the pathogenesis of certain viruses including HIV.
Alternate name: CUL-4A
Conjugation: Unconjugated
Immunogen: Synthetic peptide (ERDKDNPNQYHYVA) (746-759, C-terminus peptide), corresponding to human CUL-4A was conjugated to maleimide-activated keyhole limpet hemocyanin
Cat. #: 156385
Tool sub type: Primary antibody
Unit size: 100 ug
Research Fields: Biochemistry;Cancer;Cell biology;Genetics
Application: WB ; IP ; ChIP ; ELISA ; IHC
Target: Cullin 4A
Reactivity: Human ; Mouse
Host: Rabbit
Class: Polyclonal
Target background: CUL-4A regulates numerous key processes such as DNA repair, chromatin remodeling, spermatogenesis, haematopoiesis and the mitotic cell cycle. Moreover, CUL-4A is a core component of multiple cullin-RING-based E3 ubiquitin-protein ligase complexes which mediate the ubiquitination of target proteins. As a result, CUL-4A has been implicated in several cancers and the pathogenesis of certain viruses including HIV.
Format: Liquid
Shipping conditions: Dry ice
References:

Sharma et al. 2014. Open Biol. 4:130217. PMID: 24522884.

Shiyanov et al. 1999. J Biol Chem. 274(50):35309-12. PMID: 10585395.

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