The classical pentraxins, C-reactive protein (CRP) and serum amyloid P component (SAP) are serum opsonins, which bind to damaged membranes and nuclear autoantigens. Pentraxins are important in the process of complement activation and clearance of apoptotic bodies through FcÎ? receptors. Pentraxins are well conserved in arthropods, fish, amphibians, and mammals. In salmon, CRP/SAP-1a is reported as one of the major acute phase proteins (APPs) and were significantly up-regulated by recombinant cytokines (rIL-1Î? and rIFN-Î?) in primary head kidney cells. This is the only commercial antibody available.
| Inventor | Institute |
|---|---|
| Abdo Alnabulsi | Vertebrate Antibodies Limited |
| SKU: | 158030 |
|---|---|
| Product description: | The classical pentraxins, C-reactive protein (CRP) and serum amyloid P component (SAP) are serum opsonins, which bind to damaged membranes and nuclear autoantigens. Pentraxins are important in the process of complement activation and clearance of apoptotic bodies through FcÄÂ? receptors. Pentraxins are well conserved in arthropods, fish, amphibians, and mammals. In salmon, CRP/SAP-1a is reported as one of the major acute phase proteins (APPs) and were significantly up-regulated by recombinant cytokines (rIL-1ÄÂ? and rIFN-ÄÂ?) in primary head kidney cells. This is the only commercial antibody available. |
| Conjugation: | Unconjugated |
| Isotype: | IgG1 kappa |
| Molecular weight: | 26 |
| Immunogen: | Ovalbumin-conjugated synthetic peptide. Peptide immunogen is conserved in salmonids fish species. |
| Cat. #: | 158030 |
|---|---|
| Unit size: | 100 ug |
| Research Fields: | Cell biology;Immunology |
| Application: | ELISA ; IHC ; WB |
| Target: | Pentraxin precursor |
| Reactivity: | Salmonids |
| Host: | Mouse |
| Class: | Monoclonal |
| Target background: | The classical pentraxins, C-reactive protein (CRP) and serum amyloid P component (SAP) are serum opsonins, which bind to damaged membranes and nuclear autoantigens. Pentraxins are important in the process of complement activation and clearance of apoptotic bodies through FcÄÂ? receptors. Pentraxins are well conserved in arthropods, fish, amphibians, and mammals. In salmon, CRP/SAP-1a is reported as one of the major acute phase proteins (APPs) and were significantly up-regulated by recombinant cytokines (rIL-1ÄÂ? and rIFN-ÄÂ?) in primary head kidney cells. This is the only commercial antibody available. |
|---|
| Format: | Liquid |
|---|---|
| Shipping conditions: | Dry ice |
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