Anti-CLEC9A [8F9]

Recognises human DNGR-1, also known as CLEC9A, which is a highly specific marker of a human DC subset, as well as a receptor able to recognise a preformed signal exposed on necrotic cells.

Contributors

Institute
Cancer Research UK, London Research Institute: Lincoln's Inn Fields
Cat. #: 151707
Tool sub type: Primary antibody
Unit size: 100 ug
Research Fields: Immunology;Stem cell biology
Application: FACS ; IHC ; FACS ; IF
Target: Human DNGR1
Reactivity: Human
Clone: 8F9
Host: Mouse
Class: Monoclonal
Product description: Recognises human DNGR-1, also known as CLEC9A, which is a highly specific marker of a human DC subset, as well as a receptor able to recognise a preformed signal exposed on necrotic cells.
Conjugation: Unconjugated
Isotype: IgG2a
Immunogen: RBL-2H3 cells expressing human DNGR-1 fused to an HA epitope
Myeloma used: Sp2/0-Ag14
Target background: Recognises human DNGR-1, also known as CLEC9A, which is a highly specific marker of a human DC subset, as well as a receptor able to recognise a preformed signal exposed on necrotic cells.
Format: Liquid
Concentration: 1 mg/ml
Storage buffer: PBS with 0.02% azide
Storage conditions: -15° C to -25° C
Shipping conditions: Dry ice
References:

Poulin et al. 2010. J Exp Med. 207:1261-71. [PMID: 20479117]

Sancho et al. 2008. J Clin Invest 118:2098-110 .[PMID: 18497879]

Sancho et al. 2009. Nature. 458:899-903. [PMID: 19219027]

Canavan et al. 2018. JCI Insight. 3(23):. PMID: 30518680.

Images

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Adapted from Canavan et al. 2018. JCI Insight; 3(23). PMID

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