Anti-CLEC9A [7H11]
A rat monoclonal antibody recognising mouse DNGR-1/CLEC9A, used to study dendritic cell subsets and necrotic-cell sensing.
Contributors
| Institute |
|---|
| Cancer Research UK, London Research Institute: Lincoln's Inn Fields |
| SKU: | 151706 |
|---|---|
| Product description: | Anti-CLEC9A [7H11] is a rat monoclonal antibody that recognises mouse DNGR-1, also known as CLEC9A. It is used to detect and study CLEC9A-expressing dendritic cell subsets, supporting research into CD8a+ and CD103+ dendritic cells, antigen targeting and necrotic-cell sensing. Reported applications include ELISA, FACS, immunofluorescence, immunoprecipitation and western blot. |
| Alternate name: | C-Type Lectin Domain Family 9 Member A; HEEE9341; UNQ9341; DNGR-1; CD37; DNGR1 |
| Conjugation: | Unconjugated |
| Isotype: | IgG1 |
| Immunogen: | RBL-2H3 cells expressing mouse DNGR-1 fused to an HA epitope |
| Myeloma used: | Y3.AG.1.2.3 |
| Cat. #: | 151706 |
|---|---|
| Tool sub type: | Primary antibody |
| Unit size: | 100 ug |
| Research Fields: | Immunology;Stem cell biology |
| Application: | ELISA ; FACS ; IF ; IP ; WB |
| Target: | Mouse DNGR1 |
| Reactivity: | Mouse |
| Clone: | 7H11 |
| Host: | Rat |
| Class: | Monoclonal |
| Target background: | Recognises mouse DNGR-1, also known as CLEC9A, which is a highly specific marker of the CD8a+ and the CD103+ DC subsets, as well as a receptor able to recognise a preformed signal exposed on necrotic cells. |
|---|
| Format: | Liquid |
|---|---|
| Concentration: | 1 mg/ml |
| Storage buffer: | PBS with 0.02% azide |
| Storage conditions: | -15° C to -25° C |
| Shipping conditions: | Dry ice |
| References: |
Joffre et al. 2010. Eur J Immunol. 40:1255-65. [PMID: 20333625] Sancho et al. 2008. J Clin Invest 118:2098-110 .[PMID: 18497879] Sancho et al. 2009. Nature. 458:899-903. [PMID: 19219027] Li et al. 2015. Eur J Immunol. 45(3):854-64. PMID: 25487143. |
|---|
Images
View Gallery
Product Images
5248ffe8-ef9a-45ce-a90b-5681eb6694f7.jpg
