Anti-Claudin 16 [4C10]

Claudin16 antibody is raised using the extracellular loop 1 as an antigen.

Contributors

Institute
A*STAR Accelerate Technologies Pte Ltd
SKU: 152638
Product description: Claudin-16 (CLD16) is component of the tight junction in kidney. It is exclusively expressed in the thick ascending of limb of Henle (TALH). This is involved in the parcellular transport of Mg2+ in the TALH. Mutations in claudin-16 have been implicated in the loss of Mg in the urine. Claudin16 antibody is raised using the extracellular loop 1 as an antigen.
Alternate name: CLD16
Conjugation: Unconjugated
Isotype: IgM
Immunogen: CLD16-KLH peptide conjugate
Myeloma used: Sp2/0-Ag14
Cat. #: 152638
Tool sub type: Primary antibody
Unit size: 100 ug
Research Fields: Cell biology
Application: IF
Target: Claudin-16
Reactivity: Human
Clone: 4C10
Host: Mouse
Class: Monoclonal
Target background: Claudin-16 (CLD16) is component of the tight junction in kidney. It is exclusively expressed in the thick ascending of limb of Henle (TALH). This is involved in the parcellular transport of Mg2+ in the TALH. Mutations in claudin-16 have been implicated in the loss of Mg in the urine. Claudin16 antibody is raised using the extracellular loop 1 as an antigen.
Format: Liquid
Concentration: 0.9-1.1 mg/ml
Storage buffer: PBS with 0.02% azide
Storage conditions: -15° C to -25° C
Shipping conditions: Dry ice

Images

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Cos cells expressing exogenously expressed GFP-tagged Claudin-16 (left most pane) were immunolabelled using anti-Claudin 16 [4C10] (middle). A merge of both signals shows overlapping staining.

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