In recent years the protein has become an important biomarker and target of therapy for approximately 30% of breast cancer patients
| Institute |
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| Netherlands Cancer Institute |
| SKU: | 154731 |
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| Product description: | HER2 is a member of the human epidermal growth factor receptor (HER/EGFR/ERBB) family. Amplification or over-expression of this oncogene has been shown to play an important role in the development and progression of certain aggressive types of breast cancer. In recent years the protein has become an important biomarker and target of therapy for approximately 30% of breast cancer patients |
| Alternate name: | NEU |
| Conjugation: | Unconjugated |
| Isotype: | IgG1 |
| Molecular weight: | 185 kDa |
| Immunogen: | protein. |
| Cat. #: | 154731 |
|---|---|
| Tool sub type: | Primary antibody |
| Unit size: | 100 ug |
| Research Fields: | Cancer;Cell signaling and signal transduction |
| Application: | EM (EM) ; FACS ; IHC ; IF ; IP ; WB |
| Target: | cErbB2/HER-2 |
| Reactivity: | Human |
| Host: | Mouse |
| Class: | Monoclonal |
| Target background: | HER2 is a member of the human epidermal growth factor receptor (HER/EGFR/ERBB) family. Amplification or over-expression of this oncogene has been shown to play an important role in the development and progression of certain aggressive types of breast cancer. In recent years the protein has become an important biomarker and target of therapy for approximately 30% of breast cancer patients |
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| Format: | Liquid |
|---|---|
| Concentration: | 0.9-1.1 mg/ml |
| Storage buffer: | PBS with 0.02% azide |
| Storage conditions: | -15° C to -25° C |
| Shipping conditions: | Dry ice |
| References: |
van de Vijver et al. 1988. N Engl J Med. 319(19):1239-45. PMID: 2903446. |
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