Centrobin is a centriole-associated protein that asymmetrically localises to the daughter centriole, and is required for centriole duplication and cytokinesis.
| Inventor | Institute |
|---|---|
| Ciaran Morrison | National University of Ireland, Galway; Centre For Chromosome Biology |
| SKU: | 153779 |
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| Product description: | Centrobin is a centriole-associated protein that asymmetrically localises to the daughter centriole, and is required for centriole duplication and cytokinesis. |
| Alternate name: | Centrosomal BRCA2-interacting protein, LYST-interacting protein 8 |
| Conjugation: | Unconjugated |
| Isotype: | IgG1 kappa |
| Molecular weight: | 100 kDa (runs at c. 110 kDa on WB) |
| Immunogen: | Recombinant human centrobin amino acids 113-361 (bacterially expressed from pGEX4T as a GST fusion, then thrombin-cleaved and purified). |
| Myeloma used: | Sp2/0-Ag14 |
| Cat. #: | 153779 |
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| Tool sub type: | Primary antibody |
| Unit size: | 100 ug |
| Research Fields: | Cancer; Cell biology |
| Application: | IHC ; IF ; IP ; WB |
| Target: | Centrobin, UniProt ID:Q8N137 |
| Reactivity: | Human |
| Clone: | [6D4F4] |
| Host: | Mouse |
| Class: | Monoclonal |
| Target background: | Centrobin is a centriole-associated protein that asymmetrically localises to the daughter centriole, and is required for centriole duplication and cytokinesis. |
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| Format: | Liquid |
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| Concentration: | 1 mg/ml |
| Storage buffer: | PBS with 0.02% azide |
| Storage conditions: | -15° C to -25° C |
| Shipping conditions: | Dry ice |
| References: |
Ogungbenro et al. 2018. J Cell Biol. 217(4):1205-1215. PMID: 29440264. Centrobin controls primary ciliogenesis in vertebrates. |
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