| Inventor | Institute |
|---|---|
| Mike Price | University of Nottingham |
| SKU: | 153383 |
|---|---|
| Product description: | Cell surface glycoprotein that plays a role in cell adhesion and in intracellular signaling. Receptor for E.coli Dr adhesins, found in adenocarcinomas of endodermally derived digestive system epithelium and fetal colon. Belongs to the immunoglobulin superfamily, CEA family- contains 7 Ig-like (immunoglobulin-like) domains. |
| Alternate name: | CEACAM5; CEA; Carcinoembryonic Antigen |
| Conjugation: | Unconjugated |
| Isotype: | IgG1 |
| Molecular weight: | 84 kDa |
| Immunogen: | CEA |
| Cat. #: | 153383 |
|---|---|
| Provenance and Ownership: | The Anti-CEA [C365D3(NCRC23)] is owned by Cancer Research UK. CancerTools supplies the Anti-CEA [C365D3(NCRC23)] under licence from Cancer Research UK and is the authorised source for its distribution. Sourcing Anti-CEA [C365D3(NCRC23)] directly from the IP owner ensures authenticity, provenance and compliance with all applicable licensing and research use requirements. |
| Tool sub type: | Primary antibody |
| Unit size: | 100 ug |
| Research Fields: | Cancer; Cell signaling and signal transduction |
| Application: | ELISA ; FACS ; IHC |
| Target: | CD66e |
| Reactivity: | Human |
| Clone: | C365D3(NCRC23) |
| Host: | Mouse |
| Class: | Monoclonal |
| Target background: | Cell surface glycoprotein that plays a role in cell adhesion and in intracellular signaling. Receptor for E.coli Dr adhesins, found in adenocarcinomas of endodermally derived digestive system epithelium and fetal colon. Belongs to the immunoglobulin superfamily, CEA family- contains 7 Ig-like (immunoglobulin-like) domains. |
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| Format: | Liquid |
|---|---|
| Concentration: | 0.9-1.1 mg/ml |
| Storage buffer: | PBS with 0.02% azide |
| Storage conditions: | -15° C to -25° C |
| Shipping conditions: | Dry ice |
| References: |
Dallas et al. 2012. FASEB J. 26(6):2648-56. PMID: 22415308. Divergent roles of CD44 and carcinoembryonic antigen in colon cancer metastasis. Durrant et al. 1989. J Natl Cancer Inst. 81(9):688-96. PMID: 2468779. Flow cytometric screening of monoclonal antibodies for drug or toxin targeting to human cancer. Durrant et al. 1987. Br J Cancer. 56(4):425-32. PMID: 3689659. Quantitation of MHC antigen expression on colorectal tumours and its association with tumour progression. Durrant et al. 1986. Cancer Res. 46(7):3543-9. PMID: 3518917. Association of antigen expression and DNA ploidy in human colorectal tumors. Durrant et al. 1986. Br J Cancer. 53(1):37-45. PMID: 3947514. Antigenicity of newly established colorectal carcinoma cell lines. |
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