Cdk2 is a cell cycle protein closely related to Cdk1 (Cdc2) and a useful marker of proliferation. Cdk2 binds cyclins A and E and controls progression into S-phase.
| Inventor | Institute |
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| Julian Gannon | Cancer Research UK, London Research Institute: Clare Hall Laboratories |
| SKU: | 151244 |
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| Product description: | Cdk2 is a cell cycle protein closely related to Cdk1 (Cdc2) and a useful marker of proliferation. Cdk2 binds cyclins A and E and controls progression into S-phase. |
| Alternate name: | Cyclin-Dependent Kinase 2; Cell Division Protein Kinase 2; P33 Protein Kinase; CDKN2; CDC2-Related Protein Kinase; P33(CDK2) |
| Conjugation: | Unconjugated |
| Isotype: | IgG2a |
| Immunogen: | Human recombinant Cdk2 |
| Myeloma used: | Sp2/0-Ag14 |
| Cat. #: | 151244 |
|---|---|
| Provenance and Ownership: | The Anti-Cdk2 [AN4.3] is owned by Cancer Research UK. CancerTools supplies the Anti-Cdk2 [AN4.3] under licence from Cancer Research UK and is the authorised source for its distribution. Sourcing Anti-Cdk2 [AN4.3] directly from the IP owner ensures authenticity, provenance and compliance with all applicable licensing and research use requirements. |
| Tool sub type: | Primary antibody |
| Unit size: | 100 ug |
| Research Fields: | Cancer;Cell biology;Genetics |
| Application: | ELISA ; FACS ; IP ; WB |
| Target: | Cyclin-dependent kinase 2 (cdk2) |
| Reactivity: | Human ; Mouse ; Xenopus laevis |
| Clone: | AN4.3 |
| Host: | Mouse |
| Class: | Monoclonal |
| Target background: | Cdk2 is a cell cycle protein closely related to Cdk1 (Cdc2) and a useful marker of proliferation. Cdk2 binds cyclins A and E and controls progression into S-phase. |
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| Format: | Liquid |
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| Concentration: | 1 mg/ml |
| Storage buffer: | PBS with 0.02% azide |
| Storage conditions: | -15° C to -25° C |
| Shipping conditions: | Dry ice |
| References: |
Syafrizayanti et al. 2017. Sci Rep. 7:39756. PMID: 28045055. Personalised proteome analysis by means of protein microarrays made from individual patient samples. Chang et al. 2016. J Formos Med Assoc. :. PMID: 27773559. Immunophenotypic and genetic characteristics of diffuse large B-cell lymphoma in Taiwan. Chu et al. 2016. Journal of Fn Foods. 23:614-627 Xu et al. 2010. Biol Pharm Bull. 33(5):743-51. PMID: 20460749. Targeting the Na(+)/K(+)-ATPase alpha1 subunit of hepatoma HepG2 cell line to induce apoptosis and cell cycle arresting. Ottewell et al. 2009. Mol Cancer Ther. 8(10):2821-32. PMID: 19789217. Anticancer mechanisms of doxorubicin and zoledronic acid in breast cancer tumor growth in bone. |
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