CD9 (p24 antigen) is a unique 24 kDa transmembrane polypeptide related to the tetraspanin family. The CD9 molecule associates with other surface proteins such as a6/b4 integrin (CD49f/CD104 molecule) and HLA-DR, suggesting a role in cell adhesion, signal transduction and motility. GR21D10 is a mouse monoclonal antibody of the IgG1 isotype.
| Inventor | Institute |
|---|---|
| Francisco Ruíz-Cabello Osuna, Miguel Ángel López-Nevot and Federico Garrido Torres-Puchol, Matias Pérez Sánchez | Virgen de las Nieves University Hospital, The Andalusian Health Service |
| SKU: | 161701 |
|---|---|
| Product description: | CD9 (p24 antigen) is a unique 24 kDa transmembrane polypeptide related to the tetraspanin family. The structure of CD9 is composed of 4 transmembrane domains, with intracellular N- and C-termini. First discovered in a lymphoblastic cell line of the pre-B phenotype, CD9 was later found on platelets and their a-granules, monocytes, B-prelymphocytes, eosinophils, basophils and activated T-lymphocytes. The CD9 molecule associates with other surface proteins such as a6/b4 integrin (CD49f/CD104 molecule) and HLA-DR, suggesting a role in cell adhesion, signal transduction and motility.GR21D10 is a mouse monoclonal antibody of the IgG1 isotype. |
| Isotype: | IgG1 |
| Molecular weight: | 24 kDa |
| Immunogen: | B-ALL cells |
| Cat. #: | 161701 |
|---|---|
| Tool sub type: | Primary antibody |
| Cancer types: | Blood cancer |
| Research Fields: | Cancer |
| Application: | FACS; IHC; ELISA; WB |
| Target: | CD9 |
| Reactivity: | Human |
| Clone: | GR2110 |
| Host: | Mouse |
| Class: | Monoclonal |
| Primary citation: | Gomez-Morales et al. 1985. Hybridoma. 4(4):369-378. PMID 3864743 |
| Storage buffer: | PBS with 0.02% azide |
|---|---|
| Storage conditions: | -15° C to -25° C |
| Shipping conditions: | Dry ice |
| References: |
Gomez-Morales et al. 1985. Hybridoma. 4(4):369-378. PMID 3864743 |
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