CD63 is a member of the transmembrane 4 superfamily, also known as the tetraspanin family. These proteins mediate signal transduction events that play a role in the regulation of cell development, activation, growth, and motility. CD63 is mainly associated with membranes of intracellular vesicles, although cell surface expression may be induced.
| Institute |
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| Netherlands Cancer Institute |
| SKU: | 154733 |
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| Product description: | CD63 is a member of the transmembrane 4 superfamily, also known as the tetraspanin family. These proteins mediate signal transduction events that play a role in the regulation of cell development, activation, growth, and motility. CD63 is mainly associated with membranes of intracellular vesicles, although cell surface expression may be induced. |
| Alternate name: | Melanoma-Associated Antigen ME491; Tetraspanin-3; Granulophysin |
| Conjugation: | Unconjugated |
| Isotype: | IgG1 |
| Molecular weight: | 25 kDa |
| Immunogen: | Purified membranes of human melanoma cells |
| Myeloma used: | P3X63Ag8 |
| Cat. #: | 154733 |
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| Tool sub type: | Primary antibody |
| Unit size: | 100 ug |
| Research Fields: | Cell biology |
| Application: | ELISA ; IHC ; IP |
| Target: | CD63 |
| Reactivity: | Human |
| Host: | Mouse |
| Class: | Monoclonal |
| Target background: | CD63 is a member of the transmembrane 4 superfamily, also known as the tetraspanin family. These proteins mediate signal transduction events that play a role in the regulation of cell development, activation, growth, and motility. CD63 is mainly associated with membranes of intracellular vesicles, although cell surface expression may be induced. |
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| Format: | Liquid |
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| Concentration: | 0.9-1.1 mg/ml |
| Storage buffer: | PBS with 0.02% azide |
| Storage conditions: | -15° C to -25° C |
| Shipping conditions: | Dry ice |
| References: |
Hagen et al. 1986. Histopathology. 10(7):689-700. PMID: 2427431. Palmer et al. 1985. Pathology. 17(2):335-9. PMID: 3900899. Vennegoor et al. 1985. Int J Cancer. 35(3):287-95. PMID: 3882581. |
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