Anti-CD3 [T1P1D4*C6]

Monoclonal antibody specific for CD3 in Atlantic salmon and rainbow trout.

Contributors

Inventor Institute
Ayham Alnabulsi Vertebrate Antibodies Limited
SKU: 153303
Product description: Monoclonal antibody specific for CD3 in Atlantic salmon and rainbow trout. The CD3 complex, composed of four distinct CD3 polypeptide chains (CD3γ, CD3δ and 2X CD3Ɛ), associates with the T cell antigen receptor (TCR). It is found on all mature human T lymphocytes, NK cells and some thymocytes. CD3 is a member of the immunoglobulin superfamily, involved in antigen recognition, T lymphocyte activation and signal transduction. Anti-CD3 [T1P1D4*C6] is specific for CD3 in Atlantic salmon (Salmo salar) and rainbow trout (Oncorhynchus mykiss).
Alternate name: CD3, CD3gd, cd3g/d, cd3-gamma
Conjugation: Unconjugated
Isotype: IgG1 kappa
Immunogen: Ovalbumin-conjugated synthetic peptide- TLEYKDENTNEY
Immunogen Uniprot ID: A3RK68
Myeloma used: P3X63Ag8.653
Cat. #: 153303
Tool sub type: Primary antibody
Unit size: 100 ug
Research Fields: Cancer;Cell biology;Cell signaling and signal transduction;Immunology;Stem cell biology
Application: ELISA ; FACS ; IHC ; WB
Target: T-cell surface glycoprotein CD3 gammadelta-A chain
Reactivity: Salmon ; Rainbow Trout
Clone: T1P1D4*C6
Host: Mouse
Class: Monoclonal
Target background: Monoclonal antibody specific for CD3 in Atlantic salmon and rainbow trout. Background and Research Application The CD3 complex, composed of four distinct CD3 polypeptide chains (CD3γ, CD3δ and 2X CD3Ɛ), associates with the T cell antigen receptor (TCR). It is found on all mature human T lymphocytes, NK cells and some thymocytes. CD3 is a member of the immunoglobulin superfamily, involved in antigen recognition, T lymphocyte activation and signal transduction. Anti-CD3 [T1P1D4*C6] is specific for CD3 in Atlantic salmon (Salmo salar) and rainbow trout (Oncorhynchus mykiss).
Format: Liquid
Concentration: 1 mg/ml
Storage buffer: PBS with 0.02% azide
Storage conditions: Store at -20° C frozen. Avoid repeated freeze / thaw cycles
Shipping conditions: Dry ice
References:

Immunohistochemical examination of immune cells in adipose tissue of rainbow trout (Oncorhynchus mykiss) following intraperitoneal vaccination. Veenstra et al. 2019. Fish Shellfish Immunol. 87:559-564. PMID: 30731214.

Immunohistochemical examination of immune cells in adipose tissue of rainbow trout (Oncorhynchus mykiss) following intraperitoneal vaccination.

Images

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Flow cytometric analysis of CD3gd+ cell distribution in Rainbow Trout spleen tissue using Anti-CD3 [T1P1D4*C6]

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