Anti-CD3-associated TCR [WT31]
Contributors
| Inventor | Institute |
|---|---|
| Johan van der Vlag | Radboud University Medical Center (UMC) |
| SKU: | 160532 |
|---|---|
| Product description: | T cells are a type of immune cell, originating from hematopoietic stem cells, which are found in the bone marrow; however, the T cell matures in the thymus gland (hence the name) and plays a central role in the immune response. T cells can be distinguished from other lymphocytes by the presence of a T-cell receptor on the cell surface. |
| Conjugation: | Unconjugated |
| Isotype: | IgG1 |
| Immunogen: | human thymocytes |
| Myeloma used: | Sp2/0-Ag14 |
| Cat. #: | 160532 |
|---|---|
| Tool sub type: | Primary antibody |
| Unit size: | 100 ug |
| Research Fields: | Cancer;Immunology |
| Application: | WB |
| Target: | human thymocytes |
| Reactivity: | Human |
| Host: | Mouse |
| Class: | Monoclonal |
| Target background: | T cells are a type of immune cell, originating from hematopoietic stem cells, which are found in the bone marrow; however, the T cell matures in the thymus gland (hence the name) and plays a central role in the immune response. T cells can be distinguished from other lymphocytes by the presence of a T-cell receptor on the cell surface. |
|---|
| Format: | Liquid |
|---|---|
| Shipping conditions: | Dry ice |
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From Spits et al J Immunol September 1; 1985; 135 (3) 1922-1928. “Comparison of target antigens recognized by anti-Leu-4. WT-31 and T40/25 by electrophoresis analysis. HPR-ALL cells were iodinated with ‘”I by the iodogen method. Immunoprecipitates were prepared as described in Materials and Methods. Immunoprecipitates were subjected to electrophoresis with 5 mM iodoacetamide (nonreducing conditions) or to 5% v/v mercaptoethanol (reducing conditions) present in sample buffers. Lane A. Preformed complex preclear of lysate under nonreducing conditions. B. anti-Leu-4 under nonreducing conditions
