The CD14 antigen is a glycosylphosphatidylinositol-linked single-chain surface membrane glycoprotein with a molecular weight of 53-55 kDa. It functions as a high-affinity receptor for the lipopolysaccharide (LPS) and LPS-binding protein (LBP) complex. GRS1 is a mouse monoclonal antibody of the IgG1 isotype.
| Inventor | Institute |
|---|---|
| Francisco Ruíz-Cabello Osuna,Miguel Ángel López-Nevot and Federico Garrido Torres-Puchol, Susana Pedrinaci Rodriguez | Virgen de las Nieves University Hospital, The Andalusian Health Service |
| SKU: | 161699 |
|---|---|
| Product description: | The CD14 antigen is a glycosylphosphatidylinositol-linked single-chain surface membrane glycoprotein with a molecular weight of 53-55 kDa. It functions as a high-affinity receptor for the lipopolysaccharide (LPS) and LPS-binding protein (LBP) complex. It is found on cells of the myelomonocytic lineage. CD14 antigen is highly expressed on monocytes and macrophages, and weakly expressed on neutrophils. It is also weakly expressed on B-lymphocytes, but absent on T- and NK-lymphocytes, erythrocytes and platelets. It is found on Langerhans cells, follicular dendritic cells and histiocytes. GRS1 is a mouse monoclonal antibody of the IgG1 isotype. |
| Isotype: | IgG1 |
| Molecular weight: | 53-55 kDa |
| Immunogen: | U937 cell line |
| Cat. #: | 161699 |
|---|---|
| Tool sub type: | Primary antibody |
| Cancer types: | Blood cancer |
| Research Fields: | Cancer |
| Application: | FACS; IHC; ELISA; WB |
| Target: | CD14 |
| Reactivity: | Human |
| Clone: | GRS1 |
| Host: | Mouse |
| Class: | Monoclonal |
| Primary citation: | Knapp et al. 1990. Immunology 1991. PMCID: PMC1384357 |
| Storage buffer: | PBS with 0.02% azide |
|---|---|
| Storage conditions: | -15° C to -25° C |
| Shipping conditions: | Dry ice |
| References: |
Knapp et al. 1990. Immunology 1991. PMCID: PMC1384357 |
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