Anti-CD109 monoclonal antibody [KU43.13A]

detects CD109 antigen in several human pancreatic cancer cell lines and pancreatic cancer tissue array, with no expression in normal pancreatic tissues. It has a potential for use as diagnostic and therapeutic agent.

Contributors

Inventor Institute
Helmout Modjtahedi Kingston University
SKU: 161582
Product description: KU43.13A mAb detects CD109 antigen with high level of expression in some of the human pancreatic cell lines (e.g. BxPC-3, PANC-1, FA-6 and MIA PaCa-2)
Isotype: IgG2a
Molecular weight: 170 KDa
Immunogen: BxPC-3 cells
Cat. #: 161582
Tool sub type: Primary antibody
Research Fields: Cancer
Application: IHC, IF, IP, WB, ELISA, FACS
Target: CD109
Reactivity: Human
Clone: KU43.13A
Host: Mouse
Class: Monoclonal
Primary citation: Arias-Pinilla et al. 2018. Oncotarget. 9(28): 19994–20007. PMID: 29731998
Target background: CD109 is a glycosylphosphatidylinositol (GPI)-anchored glycoprotein that localizes to the surface of platelets, activated T-cells, and endothelial cells. It is highly expressed in cancers of various organs including the pancreas, lung, esophagus, uterine cervix, penis, and gallbladder, but hardly detectable in their normal tissues.
Shipping conditions: Dry ice
References:

Arias-Pinilla et al. 2018. Oncotarget. 9(28): 19994–20007. PMID: 29731998

Arias-Pinilla et al. 2020. Sci Rep. 10(1):537. PMID: 31953437

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