The ITGB4 gene encodes the integrin beta 4 subunit, a receptor for the laminins. This subunit tends to associate with alpha 6 subunit and is likely to play a pivotal role in the biology of invasive carcinoma.
| Inventor | Institute |
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| Arnoud Sonnenberg | Netherlands Cancer Institute |
| SKU: | 154751 |
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| Product description: | The ITGB4 gene encodes the integrin beta 4 subunit, a receptor for the laminins. This subunit tends to associate with alpha 6 subunit and is likely to play a pivotal role in the biology of invasive carcinoma. Mutations in this gene are associated with epidermolysis bullosa with pyloric atresia. |
| Alternate name: | ITGB4; GP15 |
| Conjugation: | Unconjugated |
| Isotype: | IgG2a |
| Molecular weight: | 202 kDa |
| Immunogen: | The full length CD104 protein |
| Cat. #: | 154751 |
|---|---|
| Tool sub type: | Primary antibody |
| Unit size: | 100 ug |
| Research Fields: | Cancer; Cell biology; Cell signaling and signal transduction |
| Application: | ELISA ; FACS ; IHC ; IF ; IP ; WB |
| Target: | CD104 |
| Reactivity: | Human |
| Host: | Mouse |
| Class: | Monoclonal |
| Target background: | The ITGB4 gene encodes the integrin beta 4 subunit, a receptor for the laminins. This subunit tends to associate with alpha 6 subunit and is likely to play a pivotal role in the biology of invasive carcinoma. Mutations in this gene are associated with epidermolysis bullosa with pyloric atresia. |
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| Format: | Liquid |
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| Concentration: | 0.9-1.1 mg/ml |
| Storage buffer: | PBS with 0.02% azide |
| Storage conditions: | -15° C to -25° C |
| Shipping conditions: | Dry ice |
| References: |
Geerts et al. 1999. J Cell Biol. 147(2):417-34. PMID: 10525545. |
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