A mouse monoclonal antibody recognising human casein beta subunit, used to identify terminally differentiated breast luminal epithelial cells.
| Inventor | Institute |
|---|---|
| Joy Burchell ; Joyce Taylor-Papadimitriou | Cancer Research UK, London Research Institute: Lincoln's Inn Fields |
| SKU: | 151094 |
|---|---|
| Product description: | Anti-Casein [F20.14] is a mouse monoclonal antibody that recognises the human casein beta subunit. It is used as an in vitro marker of terminally differentiated breast luminal epithelial cells, supporting studies of breast epithelial differentiation and casein expression. Reported applications include immunohistochemistry and western blot. |
| Additional notes: | F20.14 was generated using purified casein and alpha-lactalbumin as immunogen. The original Burchell et al. reference describes monoclonal antibodies to human casein, including an antibody reported to cross-react with casein and alpha-lactalbumin. |
| Conjugation: | Unconjugated |
| Isotype: | IgG1 |
| Molecular weight: | 28 kDa |
| Immunogen: | Purified casein and a-lactalbumin. |
| Myeloma used: | P3X63Ag8.653 |
| Cat. #: | 151094 |
|---|---|
| Provenance and Ownership: | The Anti-Casein [F20.14] is owned by Cancer Research UK. CancerTools supplies the Anti-Casein [F20.14] under licence from Cancer Research UK and is the authorised source for its distribution. Sourcing Anti-Casein [F20.14] directly from the IP owner ensures authenticity, provenance and compliance with all applicable licensing and research use requirements. |
| Tool sub type: | Primary antibody |
| Unit size: | 100 ug |
| Research Fields: | Cell biology |
| Application: | IHC ; WB |
| Target: | Casein beta subunit |
| Reactivity: | Human |
| Clone: | F20.14 |
| Host: | Mouse |
| Class: | Monoclonal |
| Target background: | Caseins are the major proteins found in milk. |
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| Format: | Liquid |
|---|---|
| Concentration: | 0.88 mg/ml |
| Storage buffer: | PBS with 0.02% azide |
| Storage conditions: | -15° C to -25° C |
| Shipping conditions: | Dry ice |
| References: |
Bonuccelli et al. 2012. Cell Cycle. 11(21):3972-82. PMID: 23047602. Burchell et al. 1985. Hybridoma. 4(4):341-50. PMID: 3905581. |
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