| Institute |
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| Versiti Blood Research Institute |
| SKU: | 155092 |
|---|---|
| Product description: | Von Willebrand factor (vWF) is a multimeric glycoprotein that functions in hemostasis as the initiator of platelet adhesion at the site of vascular injury and as the carrier of the anti-hemophilic factor, factor VIII (FVIII). Hereditary or acquired defects of VWF lead to von Willebrand disease (vWD), a bleeding diathesis of the skin and mucous membranes, causing nosebleeds, menorrhagia, and gastrointestinal bleeding. |
| Alternate name: | vWf |
| Conjugation: | Unconjugated |
| Molecular weight: | 250 kDa |
| Immunogen: | R/A (reduced and alkylated) fragment of vWF (see notes column) |
| Myeloma used: | P3X63Ag8.653 |
| Cat. #: | 155092 |
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| Tool sub type: | Primary antibody |
| Unit size: | 100 ug |
| Research Fields: | Immunology |
| Application: | ELISA ; WB |
| Target: | von Willebrand Factor |
| Reactivity: | Human |
| Host: | Mouse |
| Class: | Monoclonal |
| Target background: | Von Willebrand factor (vWF) is a multimeric glycoprotein that functions in hemostasis as the initiator of platelet adhesion at the site of vascular injury and as the carrier of the anti-hemophilic factor, factor VIII (FVIII). Hereditary or acquired defects of VWF lead to von Willebrand disease (vWD), a bleeding diathesis of the skin and mucous membranes, causing nosebleeds, menorrhagia, and gastrointestinal bleeding. |
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| Format: | Liquid |
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| Concentration: | 0.9-1.1 mg/ml |
| Storage buffer: | PBS with 0.02% azide |
| Storage conditions: | -15° C to -25° C |
| Shipping conditions: | Dry ice |
| References: |
Flood et al. 2018. Res Pract Thromb Haemost. 2(2):390-398. PMID: 30046743. Doruelo et al. 2017. J Thromb Haemost. 15(8):1559-1566. PMID: 28544236. Roberts et al. 2016. Blood. 127(20):2472-80. PMID: 26917779. Flood et al. 2015. Blood. 125(14):2297-304. PMID: 25662333. Flood et al. 2013. Clin Chem. 59(4):684-91. PMID: 23340442. Jacobi et al. 2012. Blood. 119(19):4543-53. PMID: 22431572. Flood et al. 2011. Blood. 117(6):e67-74. PMID: 21148813. |
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