ASICs have been shown to regulate synaptic function, fear, learning, and are one important contributor to pain and neuronal injuries.
| Inventor | Institute |
|---|---|
| Xiang-ming Zha | University of South Alabama |
| Cat. #: | 156465 |
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| Tool sub type: | Primary antibody |
| Unit size: | 100 ug |
| Research Fields: | Neurobiology |
| Application: | IHC ; WB |
| Target: | Acid-sensing ion channel (ASIC) 1a |
| Reactivity: | Mouse |
| Host: | Rabbit |
| Class: | Monoclonal |
| Product description: | Acid-sensing ion channels (ASICs) are proton-gated ion channels expressed predominantly in neurons. In the brain, the main ASIC subunits are ASIC1a, ASIC2a and ASIC2b. ASICs have been shown to regulate synaptic function, fear, learning, and are one important contributor to pain and neuronal injuries. |
|---|---|
| Conjugation: | Unconjugated |
| Immunogen: | Raised against synthetic peptide DKGVALSLDDVKRHNPC (DKG) which correlates to amino acids 479-495 of mouse ASIC1a) |
| Target background: | Acid-sensing ion channels (ASICs) are proton-gated ion channels expressed predominantly in neurons. In the brain, the main ASIC subunits are ASIC1a, ASIC2a and ASIC2b. ASICs have been shown to regulate synaptic function, fear, learning, and are one important contributor to pain and neuronal injuries. |
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| Format: | Liquid |
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| Shipping conditions: | Dry ice |
| References: |
Jiang et al. 2017. J Cereb Blood Flow Metab. 37(2):528-540. PMID: 26861816. |
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