Anti-Adiponectin [399R]

Clone 399R is used to detect plasma adiponectin concentrations. Clone 399R is also used in a combination ELISA with clone 32F8, acting as the capture antibody.

Contributors

Institute
BioServ UK Ltd
SKU: 153654
Product description: Adiponectin plays an important role in pathogenesis and amplification of insulin-resistant states in humans, where levels are reduced in patients with type-2 diabetes and obesity. (Hotta K, et al.) Clone 399R is used to detect plasma adiponectin concentrations. Clone 399R is also used in a combination ELISA with clone 32F8, acting as the capture antibody.
Alternate name: Adiponectin, 3 kDa adipocyte complement-related protein, Adipocyte complement-related 3 kDa protein, ACRP3, Adipose most abundant gene transcript 1 protein, apM-1, Gelatin-binding protein, ADIPOQ, ACDC, ACRP3, APM1, GBP28
Conjugation: Unconjugated
Isotype: IgG1
Immunogen: Synthetic peptide corresponding to the tail region of the Adiponectin molecule
Myeloma used: Sp2/0-Ag14
Cat. #: 153654
Tool sub type: Primary antibody
Unit size: 100 ug
Research Fields: Metabolism;Tissue-specific biology
Application: ELISA
Target: Adiponectin
Reactivity: Human
Clone: 399R
Host: Mouse
Class: Monoclonal
Target background: Adiponectin plays an important role in pathogenesis and amplification of insulin-resistant states in humans, where levels are reduced in patients with type-2 diabetes and obesity. (Hotta K, et al.) Clone 399R is used to detect plasma adiponectin concentrations. Clone 399R is also used in a combination ELISA with clone 32F8, acting as the capture antibody.
Format: Liquid
Shipping conditions: Dry ice
References:

Hazell, M.J. (2009) Development and Clinical Applications of Immunoassays for Human Adiponectin. Thesis. Oxford Brookes University

Miller et al. 2011. Am J Physiol Endocrinol Metab. 301(4):E659-67. PMID: 21750269.

Secretion of adipokines by human adipose tissue in vivo: partitioning between capillary and lymphatic transport.

Kiewiet et al. 2011. J Endocrinol Invest. 34(6):434-8. PMID: 20959720.

Acute effects of acylated and unacylated ghrelin on total and high molecular weight adipone…

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Assessment of specificity of the ELISA sandwich combination 399R and 32F8 to quantify adiponectin concentration in serum. Source

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